Ethanol Lock and Risk of Catheter Related Blood Stream Infection in Patients With Haemodialysis Catheter
NCT ID: NCT05953675
Last Updated: 2023-07-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
280 participants
INTERVENTIONAL
2018-08-01
2025-04-30
Brief Summary
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* The frequency of dialysis catheter-related bacteremia among patients under observation of potential complications
* Other complications of the use of hemodialysis-catheters eg. dysfunction of the catheter due to thrombosis.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Control arm
Standard procedure of isotonic saline with heparin as lock-solution
Isotonic saline with heparin
Standard procedure of isotonic saline used as lock-fluid after completed hemodialysis.
Intervention arm
3 mL of 70% ethanol as lock-solution
Ethanol 70%
Once a week, the catheter will be closed with 3 mL ethanol 70% lock-solution after a completed hemodialysis. The fluid will stay in the catheter until next hemodialysis (ca. 48 hours). The fluid will be aspirated before the hemodialysis. Standard lock-solution of isotonic saline with heparin will be used for the remaining two hemodialysis procedures of the week.
Interventions
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Ethanol 70%
Once a week, the catheter will be closed with 3 mL ethanol 70% lock-solution after a completed hemodialysis. The fluid will stay in the catheter until next hemodialysis (ca. 48 hours). The fluid will be aspirated before the hemodialysis. Standard lock-solution of isotonic saline with heparin will be used for the remaining two hemodialysis procedures of the week.
Isotonic saline with heparin
Standard procedure of isotonic saline used as lock-fluid after completed hemodialysis.
Eligibility Criteria
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Inclusion Criteria
* Currently recieving hemodialysis treatment with tunneled intravenous hemodialysis-catheter
* Written informed consent after verbal and written information is given.
Exclusion Criteria
* Intolerance to ethanol or contraindications for the use of ethanol. Eg. possible interactions, former alcohol dependency.
* Earlier infections to current catheter (exit-site, tunnel-infection and catheter-related bloodstream infection
18 Years
ALL
No
Sponsors
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Zealand University Hospital
OTHER
Responsible Party
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Principal Investigators
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Lothar Wiese, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Zealand University Hospital
Locations
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Zealand University Hospital
Roskilde, , Denmark
Countries
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Other Identifiers
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REG-184-2017
Identifier Type: -
Identifier Source: org_study_id
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