The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human

NCT ID: NCT05945394

Last Updated: 2023-09-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-01

Study Completion Date

2023-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To evaluate the association of surem TRAF3IP2 levels with the atherosclerotic plaque development in human

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Previous study had concluded that TRAF3IP2 plays a causal role in atherosclerotic plaque development and vulnerability in mice. However, no human data was available. In the present study, patients who receive coronary angiography will be enrolled. Their surem TRAF3IP2 levels will be tested using ELASA. The association of surem TRAF3IP2 levels with the atherosclerotic plaque will be evaluated.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Coronary Heart Disease, Susceptibility to, 1

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients with suspected CHD who experienced CAG

Patients with suspected coronary heart disease who experienced coronary angiography

No intervention

Intervention Type OTHER

This is an obvertional study, and there is no intervention.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

No intervention

This is an obvertional study, and there is no intervention.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Patients with suspected coronary heart disease
2. patients received coronary angiography

Exclusion Criteria

1. NYHA III-IV
2. malignant tumor
3. acute infection
4. thyroid dysfunction
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Jin Geng

associate doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ma Shuren, MD

Role: STUDY_DIRECTOR

NJMU

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Huai'an First People's Hospital

Huai'an, Jiangsu, China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Geng Jin, MD

Role: CONTACT

+86-17753124846

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Xiaozhong Yang, MD.

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

20230503

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.