Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
148 participants
OBSERVATIONAL
2023-02-23
2025-04-16
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Marfan Syndrome patients
Marfan Syndrome patients age 18-50 with a pathological FBN1 mutation
Magnetic Resonance imaging (MRI) examination
3D CINE and 4 dimensional (4D) flow MRI sequence
Healthy volunteers
Age and gender matched healthy control patients without a history of aortic disease.
Magnetic Resonance imaging (MRI) examination
3D CINE and 4 dimensional (4D) flow MRI sequence
Interventions
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Magnetic Resonance imaging (MRI) examination
3D CINE and 4 dimensional (4D) flow MRI sequence
Eligibility Criteria
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Inclusion Criteria
* Between 18-50 years of age
Exclusion Criteria
* Mental retardation
* Pregnancy, or planned pregnancy during study period
\- History of aorta disease
18 Years
50 Years
ALL
Yes
Sponsors
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Netherlands Organisation for Scientific Research
OTHER_GOV
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
OTHER
Responsible Party
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Dr. Ir. Pim van Ooij
Principal Investigator
Principal Investigators
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Pim Ooij, PhD
Role: PRINCIPAL_INVESTIGATOR
Amsterdam UMC
Locations
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Radboud University Medical Center
Nijmegen, Gelderland, Netherlands
Leiden University Medical Center
Leiden, North Holland, Netherlands
Amsterdam UMC, location AMC
Amsterdam, , Netherlands
University Medical Center Groningen
Groningen, , Netherlands
Countries
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Other Identifiers
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NL82669.018.22
Identifier Type: -
Identifier Source: org_study_id
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