Effect of Pomegranate Seed Powder on Markers of Metabolic Syndrome

NCT ID: NCT05944029

Last Updated: 2023-07-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-02-20

Study Completion Date

2023-08-24

Brief Summary

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Metabolic syndrome is a public health concern worldwide and in Pakistan as well. Abdominal obesity, hyperglycemia, hypertriglyceridemia, hypertension, and low HDL cholesterol are its hallmarks while pomegranate seed's unique chemical composition has sparked research into the health benefits in same arena as weight control, blood lipid profile changes, and other metabolic disturbances. It's high time to study therapeutic efficiency of Pomegranate seed powder against metabolic syndrome.

Detailed Description

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Metabolic syndrome, accumulation of certain metabolic risk factors, such as abdominal obesity, hyperglycemia, hypertriglyceridemia, hypertension, and low HDL cholesterol, has been noted as one of the most important risk factors for the epidemic of type 2 diabetes and cardiovascular disease in the 21st century. It has become a significant public health concern and a global epidemic with a prevalence rate of about 25% among American adults. Multiple researches have demonstrated the effectiveness of pomegranate in the management of diabetes, inflammatory conditions, obesity, and blood lipid levels, and consequently metabolic syndrome. Various pomegranate components have the potential to substitute anti-diabetic medications as well Pomegranate seed's unique chemical composition has sparked research into the health benefits, such as weight control, blood lipid profile changes, and other metabolic disorders.

seed powder can influence the patient's metabolic syndrome-related indicators.

Hypothesis:

Pomegranate seed powder can be effective to treat the individuals with impaired metabolism.

Methodology:

In a clinical trial, patients of metabolic syndrome (n=50) will be given pomegranate seed powder dose for over 8 weeks, twice a day. Biochemical outcomes including blood pressure, FBG, cholesterol, hemoglobin level will be determined before and after the completion of trial in addition to patient's weight. Finally, using one-way ANOVA and T-test, collected data will be analyzed.

Expected outcome: The study will explore the potential of pomegranate seed powder in treating metabolic syndrome's risk factors. Therefore, our findings on the studied parameters of patient will assist future researchers in developing tested, evidence-based recommendations.

Conditions

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Metabolic Syndrome

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Prospective Clinical Trial
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Metabolic syndrome Patients

Pomegranate seed powder is administered for alleviating symptoms of metabolic syndrome

Group Type EXPERIMENTAL

Pomegranate seed powder

Intervention Type DIETARY_SUPPLEMENT

10 g powder / day

Interventions

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Pomegranate seed powder

10 g powder / day

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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Punica granatum

Eligibility Criteria

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Inclusion Criteria

* BMI \> 25kg/m2
* Dyslipidemia
* Altered blood glucose level
* Age 30-55 ( male and female)

Exclusion Criteria

* Thyroid disorder
* Liver disease
* Kidney disorder
* Cancer etc
Minimum Eligible Age

30 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Asif Ali

OTHER

Sponsor Role lead

Responsible Party

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Asif Ali

Researcher

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Dr. Asif Ali, Mphil

Role: STUDY_DIRECTOR

University of Veterinary and Animal Sciences Lahore

Locations

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University of Veterinary and Animal sciences Lahore

Lahore, Punjab Province, Pakistan

Site Status RECRUITING

Countries

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Pakistan

Central Contacts

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Shahbano Zahid, Mphil

Role: CONTACT

+923095563643

Dr. Asif Ali, PhD

Role: CONTACT

+923017151530 ext. 296

Facility Contacts

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Dr. Asif Ali, PhD

Role: primary

03017151530 ext. 296

Provided Documents

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Document Type: Study Protocol, Statistical Analysis Plan, and Informed Consent Form

View Document

Other Identifiers

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UVAS

Identifier Type: -

Identifier Source: org_study_id

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