US National OCS Heart Perfusion (OHP) Registry

NCT ID: NCT05915299

Last Updated: 2025-10-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-25

Study Completion Date

2033-08-31

Brief Summary

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This Registry is a sponsor initiated, multi-center, observational post-approval registry with independent academic oversight.

Detailed Description

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The objective of this US National OHP Registry is to collect data on the post-transplant clinical outcomes of all donor hearts preserved and assessed on the OCS Heart System and to document the performance of the OCS Heart device in the real-world setting after FDA approval in the US.

The US National OHP Registry will enroll all heart transplant recipients who are transplanted with an OCS-perfused donor heart in the Registry. Patients' clinical outcomes will be followed up to five years post-transplant, loss to follow up, or death, whichever occurs first.

Conditions

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Heart Transplant

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Study Groups

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OCS Heart Transplant Recipients

All heart transplant recipients who are transplanted with an OCS perfused donor heart are eligible for this registry.

OCS Heart

Intervention Type DEVICE

The TransMedics® Organ Care System (OCS) Heart System is an FDA approved portable extracorporeal heart perfusion and monitoring system.

The OCS Heart System's innovative technology was designed to comprehensively overcome the historical limitations of cold storage. The OCS Heart System expands the utilization of donor hearts by enabling the use of donor hearts deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of cold static cardioplegic preservation.

Interventions

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OCS Heart

The TransMedics® Organ Care System (OCS) Heart System is an FDA approved portable extracorporeal heart perfusion and monitoring system.

The OCS Heart System's innovative technology was designed to comprehensively overcome the historical limitations of cold storage. The OCS Heart System expands the utilization of donor hearts by enabling the use of donor hearts deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of cold static cardioplegic preservation.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* N/A

Exclusion Criteria

* N/A
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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TransMedics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Banner University Medical Center Phoenix

Phoenix, Arizona, United States

Site Status RECRUITING

University of California San Diego

La Jolla, California, United States

Site Status RECRUITING

Lucile Packard Children's Hospital Stanford

Palo Alto, California, United States

Site Status RECRUITING

Stanford University

Palo Alto, California, United States

Site Status RECRUITING

University of California San Francisco

San Francisco, California, United States

Site Status RECRUITING

Boulder

Boulder, Colorado, United States

Site Status RECRUITING

Yale New Haven Hospital

New Haven, Connecticut, United States

Site Status RECRUITING

Mayo Clinic Florida

Jacksonville, Florida, United States

Site Status RECRUITING

Tampa General Hospital

Tampa, Florida, United States

Site Status RECRUITING

Emory University Hospital

Atlanta, Georgia, United States

Site Status RECRUITING

University of Chicago

Chicago, Illinois, United States

Site Status RECRUITING

University of Kentucky

Lexington, Kentucky, United States

Site Status RECRUITING

Tufts Medical Center

Boston, Massachusetts, United States

Site Status RECRUITING

Massachusetts General Hospital

Boston, Massachusetts, United States

Site Status RECRUITING

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Site Status RECRUITING

University of Michigan

Ann Arbor, Michigan, United States

Site Status RECRUITING

Henry Ford

Detroit, Michigan, United States

Site Status RECRUITING

Minneapolis Heart Institute

Minneapolis, Minnesota, United States

Site Status RECRUITING

University of Minnesota

Minneapolis, Minnesota, United States

Site Status RECRUITING

Mayo Clinic Rochester

Rochester, Minnesota, United States

Site Status RECRUITING

Mount Sinai

New York, New York, United States

Site Status RECRUITING

Columbia University Irving Medical Center/ New York Presbyterian Hospital

New York, New York, United States

Site Status RECRUITING

Montefiore

The Bronx, New York, United States

Site Status RECRUITING

Westchester Medical Center

Valhalla, New York, United States

Site Status RECRUITING

University of North Carolina

Chapel Hill, North Carolina, United States

Site Status RECRUITING

Atrium Health

Charlotte, North Carolina, United States

Site Status RECRUITING

Duke University

Durham, North Carolina, United States

Site Status RECRUITING

The Christ Hospital

Cincinnati, Ohio, United States

Site Status RECRUITING

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Site Status RECRUITING

Medical University of South Carolina

Charleston, South Carolina, United States

Site Status RECRUITING

Baylor Scott and White

Dallas, Texas, United States

Site Status RECRUITING

University of Texas Southwestern

Dallas, Texas, United States

Site Status RECRUITING

University of Utah

Salt Lake City, Utah, United States

Site Status RECRUITING

Virginia Commonwealth University Health

Richmond, Virginia, United States

Site Status RECRUITING

University of Washington Medical Center

Seattle, Washington, United States

Site Status RECRUITING

Aurora St Luke's Medical Center

Milwaukee, Wisconsin, United States

Site Status RECRUITING

Froedtert & the Medical College of Wisconsin

Milwaukee, Wisconsin, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Raicca Haqqi

Role: CONTACT

9788090620

Kausar Qidwai

Role: CONTACT

Facility Contacts

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Raelyn McGarry

Role: primary

Andrew Stewart

Role: primary

858-534-3793

Tiffany Koyano

Role: primary

Tiffany Koyano

Role: primary

650-724-6921

Cassie Nguyen

Role: primary

415-353-9124

Cherry Ng

Role: backup

Nargis Kalia, MPH

Role: primary

Wasima Shinwari

Role: primary

518-414-0322

Mauricia Buchanan

Role: primary

904-953-9455

Courtney Nicholas

Role: primary

813-844-4914

Sara Hobbs

Role: primary

941-465-0829

Kayla Moore

Role: primary

773-702-8228

Jennifer Isaacs

Role: primary

859-323-4738

Gaurav Das

Role: primary

Kamila Drezek

Role: primary

617-724-2610

Debbie Conboy

Role: primary

617-632-8135

China Green

Role: primary

Amanda Kasperek

Role: backup

7349369664

Matthew Callaghan

Role: primary

313-916-4596

Molly Fuller

Role: primary

612-863-7493

Monica Myers

Role: primary

612-301-1175

Deborah Rolbiecki

Role: primary

507-255-5027

Jolene Erola

Role: backup

Favio Herbas

Role: primary

Bo Lu

Role: primary

Agnieszka Siemienik

Role: primary

Corazon DeLaPena

Role: primary

Briana Clark

Role: primary

919-966-7108

Susan Bernardo

Role: primary

Sarah Casalinova

Role: primary

919-613-5621

William Stewart

Role: primary

Gail Wallen

Role: primary

412-647-2782

Morgan Overstreet

Role: primary

843-792-8896

Lesia Parker

Role: primary

214-820-4836

Hadi Beaini

Role: primary

214-648-9472

Ashley Elmer

Role: primary

801-585-6775

Giorgi Mchedkushvili

Role: primary

Jinfeng Han

Role: backup

Shauna Andrus

Role: primary

206-953-9970

Jillian Lux

Role: primary

Kelly Potzner

Role: primary

Other Identifiers

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OCS-HEART-OHP-II

Identifier Type: -

Identifier Source: org_study_id

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