Machine Vision Based MDS-UPDRS III Machine Rating

NCT ID: NCT05906719

Last Updated: 2023-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

871 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-01

Study Completion Date

2024-04-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The Movement Disorders Society (MDS) Unified Parkinson's Disease Rating Scale (UPDRS) Part III (MDS-UPDRS III) is the primary assessment method for motor symptoms in Parkinson's disease patients. Currently, movement disorder specialists conduct semi-quantitative scoring, which entails limitations such as subjectivity, weak sensitivity, and a limited number of professional physicians. This study, based on machine vision, establishes gold standard labels according to expert scoring. By using machine learning, we develop a machine rating model and compare the model's performance with gold standard rating and general clinical rating to investigate the accuracy of machine vision-based MDS-UPDRS III machine rating.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Parkinsonian Disorders Machine Learning

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

video recording

Patients' performance of MDS-UPDRS III will be recorded.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Meeting the diagnostic criteria for Parkinsonism established by the International Movement Disorder Society: having bradykinesia, and meeting at least one of the two criteria for resting tremor or muscle rigidity
* 20 to 80 years old
* Good compliance, voluntarily joining the study, and able to sign an informed consent form or have it signed by a legal representative

Exclusion Criteria

* Significant cognitive impairment (MMSE ≤ 23)
* Unable to sign written informed consent or unable to complete the trial due to other reasons
* Other situations in which the researcher deems the participant unsuitable for this study
* Participation in other clinical trials
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Second Affiliated Hospital of Soochow University

OTHER

Sponsor Role collaborator

Beijing Hospital

OTHER_GOV

Sponsor Role collaborator

Beijing Tiantan Hospital

OTHER

Sponsor Role collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

Sponsor Role collaborator

Fujian Medical University Union Hospital

OTHER

Sponsor Role collaborator

Guangdong Provincial People's Hospital

OTHER

Sponsor Role collaborator

West China Hospital

OTHER

Sponsor Role collaborator

Ruijin Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Center for Movement Disorders, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Beijing Hospital, Neurology Department

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Department of Neurology, Fujian Medical University Union Hospital

Fuzhou, Fujian, China

Site Status NOT_YET_RECRUITING

Department of Neurology, Guangdong Neuroscience Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences

Guangzhou, Guangdong, China

Site Status NOT_YET_RECRUITING

Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Site Status NOT_YET_RECRUITING

Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University

Suzhou, Jiangsu, China

Site Status NOT_YET_RECRUITING

Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Department of Neurology, West China Hospital, Sichuan University

Chengdu, Sichuan, China

Site Status NOT_YET_RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Lun Liu, MD,PhD

Role: CONTACT

021-86-64370045

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Tao Feng, MD

Role: primary

86-010-59976611

Wen Su, MD

Role: primary

86-010-85132266

Qinyong Ye, MD

Role: primary

86-0591-83357896

Lijuan Wang, MD

Role: primary

86-020-83827812

Tao Wang, MD

Role: primary

86-027-85726114

Chunfeng Liu, MD

Role: primary

86-0512-68282030

Jun Liu, MD,PhD

Role: primary

86-021-64370045

Huifang Shang, MD

Role: primary

86-028-85422114

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

u3

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.