Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity

NCT ID: NCT05882084

Last Updated: 2023-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-24

Study Completion Date

2023-12-31

Brief Summary

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This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.

Detailed Description

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Conditions

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Photoaging

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Astaxanthin vs Placebo
Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Astaxanthin

6 mg daily

Group Type EXPERIMENTAL

Astaxanthin 6 mg daily

Intervention Type DIETARY_SUPPLEMENT

Astaxanthin at 6 mg is given for daily ingestion and compared against placebo.

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Placebo

Interventions

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Astaxanthin 6 mg daily

Astaxanthin at 6 mg is given for daily ingestion and compared against placebo.

Intervention Type DIETARY_SUPPLEMENT

Placebo

Placebo

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Females who are 30 to 55 years of age
* Half of the women will have Fitzpatrick skin type 1-3 and the other half of the women will have Fitzpatrick skin type 4-6

Exclusion Criteria

* Individuals with a known allergy to astaxanthin or other carotenoids (such as zeaxanthin, lutein, lycopene).
* Individuals who are unwilling to discontinue carotenoid supplementation for at least 1 month prior to enrollment
* Individuals unwilling to restrict intake of foods like shrimp, salmon, mangos, carrots, and tomatoes during the study.
* New supplementation within 4 weeks with tocopherol
* Individuals who are unwilling to stay consistent with a facial cleansing regimen.
* Those who are unwilling to discontinue topical hydroquinone, retinoid or benzoyl peroxide for 2 weeks prior to enrollment
* Individuals who are pregnant or breastfeeding.
* Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
* Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years
Minimum Eligible Age

30 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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AstaReal

UNKNOWN

Sponsor Role collaborator

Integrative Skin Science and Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Raja Sivamani, MD MS AP

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Raja Sivamani, MD

Role: PRINCIPAL_INVESTIGATOR

Integrative Skin Science and Research

Locations

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Integrative Skin Science and Research

Sacramento, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Raja Sivamani, MD

Role: CONTACT

916-524-1216

Facility Contacts

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Nasima Afzal

Role: primary

916-750-2463

Other Identifiers

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Asta_Skin_01

Identifier Type: -

Identifier Source: org_study_id

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