Application of Biomarkers in Neurological Diseases

NCT ID: NCT05881226

Last Updated: 2024-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-05

Study Completion Date

2031-12-01

Brief Summary

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To explore the predictive and diagnostic role of biomarkers in patients with neurological diseases.

Detailed Description

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With the rise and continuous development of omics technology and bioinformatics technology, some scholars have applied proteomics technology and metabolomics technology to study the brain tissue, plasma and CSF of patients with nervous system diseases, so as to screen out potential biomarkers, with a view to providing new research ideas for pathogenesis and early diagnosis of neurological diseases. At present, the research on some novel biomarkers is still in its infancy, and many key problems remain to be solved. It is necessary to further determine the expression level of biomarkers in normal human body and the characteristics of biomarkers in patients with neurological diseases.

Conditions

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Biomarkers

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients admitted to hospital/emergency department with neurological diseases

All clinical data, laboratory data and imaging data of patients at baseline and follow-up were collected, as well as blood and tissue samples that did not affect the diagnosis and treatment of patients after obtaining the consent of patients at different time points in the acute and chronic phases.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Patients with neurological diseases;
2. Subjects or legal agents agree to participate in the study and sign the informed consent.

Exclusion Criteria

1. Participating in other clinical investigators;
2. Unwilling to be followed up or poor treatment compliance;
3. Other conditions considered unsuitable for inclusion by the researchers.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Yi Yang

OTHER

Sponsor Role lead

Responsible Party

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Yi Yang

Associated Dean of First Hospital of Jilin University

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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First Hospital of Jilin University

Changchun, Jilin, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yi YY Yang, Ph.D.

Role: CONTACT

18186872986 ext. 86

Zhen-Ni GZ GUO, M.D.

Role: CONTACT

18186872986 ext. 86

Facility Contacts

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Yi Yang, MD, PhD

Role: primary

Other Identifiers

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Bio-Neuro

Identifier Type: -

Identifier Source: org_study_id

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