Equivalent Glycemic Load and Insulinemic Response Elicited by 7 Low Carbohydrate Products in Healthy Adults

NCT ID: NCT05870891

Last Updated: 2025-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-06-15

Study Completion Date

2023-10-27

Brief Summary

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The purpose of this study is to test the hypothesis that the equivalent glycemic load (EGL) value of portions of white bread containing 5 g available carbohydrate measured in this study is accurate and precise to within 1 gram. Additionally, the EGL of 7 low carbohydrate foods will be measured to determine their glycemic impact.

Detailed Description

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Conditions

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Healthy Nutrition

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Peanut Butter Cereal

Consumption of Peanut Butter Cereal

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

Cinnamon Almond Cereal

Consumption of Cinnamon Almond Cereal

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

Sriracha Crisps

Consumption of Sriracha Crisps

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

Cheddar Crisps

Consumption of Cheddar Crisps

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

Almond Blueberry Butter Bar

Consumption of Almond Blueberry Butter Bar

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

Peanut Butter and Dark Chocolate Bar

Consumption of Peanut Butter and Dark Chocolate Bar

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

Almond Dark Chocolate Bar

Consumption of Almond Dark Chocolate Bar

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

White Bread 5 g available carbohydrate

Consumption of white bread containing 5 g available carbohydrate

Group Type EXPERIMENTAL

Food

Intervention Type OTHER

Food

White Bread 20 g available carbohydrate

Consumption of white bread containing 20 g available carbohydrate

Group Type ACTIVE_COMPARATOR

Food

Intervention Type OTHER

Food

Interventions

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Food

Food

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18-75 inclusive
* Willing to abstain from unusual strenuous exercise and consuming alcoholic drinks for 24 hours before study days
* Willing to refrain from smoking tobacco or marijuana for 12h before and during study visits
* Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator
* Subjects must be eligible to receive income in Canada and be covered by a health insurance plan such as OHIP

* Pregnant or lactating individuals
* Personal history of diabetes
* Major trauma or surgical event within 3 months of screening
* The presence of any laboratory result, health condition, illness or drug use that increases risk to the subject or to others or may affect the results, as judged by the Qualified Investigator
* Unwillingness or inability to comply with experimental procedures and to follow INQUIS safety guidelines
* Known intolerance, sensitivity, or allergy to any ingredients in the study test meals. All allergens should be assumed to be a result of manufacturing practices.
* Subject is currently participating or recently (within 30 days of screening) participated in a clinical trial involving long-term exposure (greater than 24 hours) to an investigational drug, nutritional supplement or lifestyle modification
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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INQUIS Clinical Research

INDUSTRY

Sponsor Role collaborator

General Mills

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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INQUIS Clinical Research, Ltd.

Toronto, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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INQ-2324

Identifier Type: -

Identifier Source: org_study_id

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