Estimation of the Tissue and Serum Levels of Interleukin (IL) -35 in Mycosis Fungoides: a Case Control Study

NCT ID: NCT05855460

Last Updated: 2023-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-12

Study Completion Date

2023-06-30

Brief Summary

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Tissue and serum samples from 20 MF patients and 20 normal healthy controls will be subjected for biochemical assessments by ELISA (Enzyme- linked immune-sorbent assay) for assessing the level of IL35.

Detailed Description

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Tissue and serum samples from 20 MF patients and 20 normal healthy controls will be subjected for biochemical assessments by ELISA (Enzyme- linked immune-sorbent assay) for assessing the level of IL35

Conditions

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Mycosis Fungoides

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Mycosis fungoides patients

Blood sample and skin biopsy for assessment of IL35 by ELISA

Skin biopsy

Intervention Type DIAGNOSTIC_TEST

biochemical assessment for measurement IL35 by ELISA (Enzyme linked immunosorbent assay) technique in tissue and serum samples of all thirty patients and healthy controls.

Normal healthy controls

Blood sample and skin biopsy for assessment of IL35 levels by ELISA

Skin biopsy

Intervention Type DIAGNOSTIC_TEST

biochemical assessment for measurement IL35 by ELISA (Enzyme linked immunosorbent assay) technique in tissue and serum samples of all thirty patients and healthy controls.

Interventions

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Skin biopsy

biochemical assessment for measurement IL35 by ELISA (Enzyme linked immunosorbent assay) technique in tissue and serum samples of all thirty patients and healthy controls.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Blood sample

Eligibility Criteria

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Inclusion Criteria

* Patients with mycosis fungoides. Both genders. Age group ≥ 18 years old.

Exclusion Criteria

* Patients with any other skin diseases. Patients who received treatments for mycosis fungoides in the past three months.

Subjects with history of solid or hematological malignancy as leukemia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Maha Fathy Elmasry

Maha Fathy Elmasry, MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Maha Fathy Elmasry, MD

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

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Cairo University

Giza, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Sally Doss, MD

Role: CONTACT

01223283288

Facility Contacts

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Sally Doss

Role: primary

01223283288

Other Identifiers

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Yasmfil35

Identifier Type: -

Identifier Source: org_study_id

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