Assessment of Circulating Fubctional Mitochondrias in Vitiligo Patients

NCT ID: NCT05525741

Last Updated: 2024-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

59 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-19

Study Completion Date

2025-06-30

Brief Summary

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To compare the level of circulating functional mitochondria in the serum of vitiligo patients as compared to controls

Detailed Description

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Conditions

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Skin and Connective Tissue Diseases

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Patients with non segmental vitiligo compared to healthy volunteers (1st degree family of vitiligo patients) atopic dermatitis, psoriasis and alopecia areata patients
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Vitiligo Group

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Group Type EXPERIMENTAL

Non segmental vitiligo

Intervention Type OTHER

The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit.

The Investigator:

* Inform the subject of the goals, constraints and risks of the study and obtain written consent.
* Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including.

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Volunteers Group

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Group Type OTHER

Health Volunteers

Intervention Type OTHER

The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. The family control subjects will be recruited from the vitiligos patients coming into our department. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit.

The Investigator:

* Inform the subject of the goals, constraints and risks of the study and obtain written consent.
* Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including.

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Interventions

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Health Volunteers

The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. The family control subjects will be recruited from the vitiligos patients coming into our department. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit.

The Investigator:

* Inform the subject of the goals, constraints and risks of the study and obtain written consent.
* Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including.

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Intervention Type OTHER

Non segmental vitiligo

The subjects will be selected from among those presenting for the consultation or hospitalization of the Dermatology department of the CHU de Nice. All necessary information will be given to the subjects and a briefing note will be given to them. A reflection period will be left for the subjects to sign the informed consent, and if necessary, another appointment will be scheduled for the inclusion visit.

The Investigator:

* Inform the subject of the goals, constraints and risks of the study and obtain written consent.
* Conduct an examination of the subject's medical history Will verify that the subject meets all inclusion criteria and does not present any of the criteria for not including.

If the subject consents and they meet all the criteria a 20 ml blood sample will be taken.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with non segmental vitiligo,
* atopic dermatitis, psoriais, alopecia areata,
* 1st degree relative of vitiligo patients.

Exclusion Criteria

* segmental or mixed vitiligo,
* personnal history of other autoimmune disorders,
* oral use of antioxidant,
* pregant women
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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passeron thierry, PhD

Role: PRINCIPAL_INVESTIGATOR

CHU de Nice, Service de Dermatologie

Locations

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CHU de Nice - Hôpital de l'Archet

Nice, Alpes-maritimes, France

Site Status

Countries

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France

Other Identifiers

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22-PP-10

Identifier Type: -

Identifier Source: org_study_id