Cognitive Functions in Breastfed Preschool Children

NCT ID: NCT05846828

Last Updated: 2023-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-01

Study Completion Date

2025-02-01

Brief Summary

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The current work aims to assess of the cognitive development in breastefed children and compare it with artificially fed children as well as the duration of breastfeeding.

Detailed Description

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Breastfeeding provides nutritional and immunological benefits to infants and also prevents infections . Breastfeeding also has clear short-term benefits for child survival through reduction of morbidity and mortality from infectious diseases. Breastfeeding also has longterm benefits .Breastfeeding improves cognitive development and emotional interactions between the mother and infant .A previous meta-analysis of 20 studies that compared breastfeeding with formula-feeding reported that breastfeeding is associated with significantly improved cognitive development from infancy to adolescence .The results of a meta-analysis of these studies showed that breastfeeding was associated with an increase of 3•5 points (95% CI 1•9-5•0) on intelligence tests at childhood and adolescence. This beneficial effect of breastfeeding could be due to the presence of long-chain polyunsaturated fatty acids, such as arachidonic acid and docosahexaenoic acid in breast milk . Breastfed infants have higher concentrations of these fatty acids that are positively associated with brain development .

Child cognitive development is influenced by genetic and environmental factors . The child has a genetically determined potential for cognitive development. However environmental factors, such as adequate nutrition and the parents' ability to create a good and stimulating home environment may also have a positive influence on the child's cognitive development .Several studies have shown a positive correlation between breast feeding and cognitive development in children . In this study we measure the mental development of children by the use of Stanford binet intelligence test. It is a cognitive and intelligence test that is used diagnose developmental and intellectual deficiencies in young children .

Other risk factors affecting children's mental development should be taken in consideration like the mothers' age, educational level (lower than high school, high school diploma, college degree, university degree, and higher than a university degree), family income, job status (employed/unemployed), sex of infant, gestational age, and infant birth weight.

Conditions

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Breast Feeding

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Stanford Binet IQ test

The Fourth Edition Stanford-Binet test which is based upon a four-factor model of intelligence, and its 15 subtests are partitioned into :

1. Verbal ability.
2. Abstract/Visual ability.
3. Quantaitive potential.
4. Short-Term Memory Scales

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Children more than 3 years and till age of 5 years that present to Assiut University Hospital with acute diseases.

Exclusion Criteria

1. Children known to have chronic disease.
2. Chidren with History of birth anoxia, birth trauma, kernictrus, epilepsy, metabolic diseases.
3. Positive family history of mental retardation.
Minimum Eligible Age

3 Years

Maximum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Romany Eissa Atya Eissa

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Emad EL-Deen Mahmoud Hammad, prof

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Amr Mohamed Kotb, lecturer

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Central Contacts

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Romany Eissa Atya

Role: CONTACT

01221695657

References

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Golding J, Rogers IS, Emmett PM. Association between breast feeding, child development and behaviour. Early Hum Dev. 1997 Oct 29;49 Suppl:S175-84. doi: 10.1016/s0378-3782(97)00062-5.

Reference Type BACKGROUND
PMID: 9363425 (View on PubMed)

Fergusson DM, Beautrais AL, Silva PA. Breast-feeding and cognitive development in the first seven years of life. Soc Sci Med. 1982;16(19):1705-8. doi: 10.1016/0277-9536(82)90096-x.

Reference Type BACKGROUND
PMID: 7178917 (View on PubMed)

Lee H, Park H, Ha E, Hong YC, Ha M, Park H, Kim BN, Lee B, Lee SJ, Lee KY, Kim JH, Jeong KS, Kim Y. Effect of Breastfeeding Duration on Cognitive Development in Infants: 3-Year Follow-up Study. J Korean Med Sci. 2016 Apr;31(4):579-84. doi: 10.3346/jkms.2016.31.4.579. Epub 2016 Feb 22.

Reference Type BACKGROUND
PMID: 27051242 (View on PubMed)

Other Identifiers

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breastfeeding and IQ

Identifier Type: -

Identifier Source: org_study_id

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