Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium

NCT ID: NCT05835141

Last Updated: 2025-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-01

Study Completion Date

2024-05-31

Brief Summary

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To determine what proportion of patients have inferior angle recess dimensions that could accommodate the OTX-TIC, and what are risk factors for implant contact with the corneal endothelium.

Detailed Description

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Conditions

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Corneal Endothelium

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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OCT Imaging

Each participant will receive imaging of the inferior sectors of the iridocorneal angle at 150°, and 180°, and 210° with the swept-source ANTERION AS-OCT system under standardized light and dark lighting conditions by a trained research technician

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age over 40 years
* No history of ocular surgery other than cataract surgery

Exclusion Criteria

\- Media opacities that preclude OCT imaging of the anterior segment
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Southern California

OTHER

Sponsor Role lead

Responsible Party

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Benjamin Xu

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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USC Roski Eye Institute

Los Angeles, California, United States

Site Status

Countries

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United States

Other Identifiers

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The XU Study

Identifier Type: -

Identifier Source: org_study_id

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