Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
480 participants
OBSERVATIONAL
2020-01-01
2025-07-12
Brief Summary
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Also, we will clarify the relationship between sensory phenotypes and social impairment by two specific sensory-social paradigms targeting eye gaze avoidance and social touch anxiety, as well as the atypical neural representation of ASD during eye gaze and viewing social touch by fMRI and EEG.
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Detailed Description
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1. Establish sensory phenotypes of a Taiwanese ASD cohort across lifespan, including variety of sensory modalities (i.e., visual, tactile, auditory, smell/taste, proprioception, etc.), sensory domains (i.e., low registration, sensory seeking, sensory sensitivity, and sensory avoiding), and clinical correlates.
2. Clarify the relationship between sensory phenotypes and social impairment by two specific sensory-social paradigms targeting eye gaze avoidance and social touch anxiety, which are hallmarks of ASD. Factors of emotion types as well as familiarity of faces or social/object touch will be manipulated to examine how they moderate eye tracking and pupil response.
3. Identify the atypical neural representation of ASD during eye gaze and viewing social touch by fMRI and EEG.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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ASD Group
ASD participants, no intervention
no intervention
no intervention
TD Group
TD participants, no intervention
no intervention
no intervention
Interventions
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no intervention
no intervention
Eligibility Criteria
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Inclusion Criteria
ASD group:
* Diagnosis of autism spectrum disorder
* Age above 12-40 years old
* No diagnosis of autism spectrum disorder
* Age above 12-40 years old
Exclusion Criteria
* Pregnant woman
* Metal implant in the body
TD group:
* History of major psychiatric disorders
* Pregnant woman
* Metal implant in the body
18 Months
ALL
Yes
Sponsors
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National Taiwan University Hospital
OTHER
Responsible Party
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Principal Investigators
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Yi Ling Chien
Role: PRINCIPAL_INVESTIGATOR
National Taiwan University Hospital
Locations
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National Taiwan University Hospital
Taipei, , Taiwan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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201903126RINA
Identifier Type: -
Identifier Source: org_study_id
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