Racial Discrimination and Stress Response

NCT ID: NCT05820659

Last Updated: 2025-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

144 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-06-29

Study Completion Date

2024-11-17

Brief Summary

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The goal of this study is to learn about whether ethnic minority adolescents' racial discrimination experience is related to dysregulated biological responses to subtle racism, and how the relationship may be attenuated or exacerbated by a set of social and cognitive factors. The main questions it aims to answer are:

* to reveal the relationship between racial discrimination experiences and ethnic minority adolescents' stress response to subtle racism
* to test parental ethnic-racial socialization, children's attribution to subtle racism and their racial identity as potential risk and protective factors.

Detailed Description

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Racial discrimination experiences constitute significant risks for ethnic minority youth's physical and mental health problems. One explanation poses that chronic stress can lead to altered, dysregulated stress responses, which can make individuals susceptible to health problems. Currently, there is no experimental study that comprehensively measure ethnic minority youth's stress response to subtle racism, or investigate the contributing roles of racial discrimination experience and possible risk and protective factors.

A community sample of 9-14-year-old ethnic minority adolescents (40 Latino American, 40 Black/African American) and their parents will be recruited. The study employs an adapted peer rejection task which has been widely used with youth, and carefully designed to elicit the experience of subtle racial discrimination from White peers. Adolescents' cardiovascular activity and saliva samples will be taken at multiple time points before, during, and after the peer rejection task, tapping on response involving hypothalamic-pituitary-adrenal (HPA) axis, autonomic nervous system (ANS), and inflammatory mediator (IM). Adolescents will report their racial discrimination experience, make attribution about the peer rejection experience, report emotional experience, and rate their racial identity. Adolescents will complete an impossible puzzle task to elicit cognitive stress, during which they will be asked to fit all puzzle pieces into a wooden frame with a wrong piece provided. Their cardiovascular activity, attribution, and emotional experience in response to the impossible puzzle task will be measured. Parents will complete a questionnaire to report their ethnic-racial socialization practices.

The goals of this proposal are: 1) Reveal the relationship between racial discrimination experiences and ethnic minority adolescents' stress response to subtle racism as well as to cognitive stress; and 2) Test parental ethnic-racial socialization, children's attribution to subtle racism and their racial identity as potential risk and protective factors.

Conditions

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Stress Reaction; Acute

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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stress inducing task

Adolescents will complete an adapted peer rejection task on the computer to elicit the experience of subtle racial discrimination from White peers, as well as an impossible puzzle task to elicit cognitive stress.

Group Type EXPERIMENTAL

peer rejection task and impossible puzzle task

Intervention Type BEHAVIORAL

Peer rejection task: Adolescents will be informed that two peers will take turns to choose who they will chat with for different topics. Participants will not be chosen by virtual White peers 75% of the time. In reality, White peers are computerized avatars and whether or not adolescents are chosen by those peers is programmed with PsychoPy software.

Impossible puzzle task: Adolescents will be asked to fit all puzzle pieces into a wooden frame with a wrong piece provided.

Interventions

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peer rejection task and impossible puzzle task

Peer rejection task: Adolescents will be informed that two peers will take turns to choose who they will chat with for different topics. Participants will not be chosen by virtual White peers 75% of the time. In reality, White peers are computerized avatars and whether or not adolescents are chosen by those peers is programmed with PsychoPy software.

Impossible puzzle task: Adolescents will be asked to fit all puzzle pieces into a wooden frame with a wrong piece provided.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 9-14 years old
* identified as Latino American or Black/African American
* Living in Warren county of Kentucky
* Parents of eligible adolescents

Exclusion Criteria

Adolescents will not participate in the peer rejection task when they report to have:

* frequent experiences of peer victimization
* frequent experiences of racial discrimination
* severe depression
* severe social anxiety disorder
* severe generalized anxiety disorder
Minimum Eligible Age

9 Years

Maximum Eligible Age

69 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Western Kentucky University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Qingfang Song, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Western Kentucky University

Locations

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Western Kentucky University

Bowling Green, Kentucky, United States

Site Status

Countries

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United States

References

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Lucas T, Wegner R, Pierce J, Lumley MA, Laurent HK, Granger DA. Perceived Discrimination, Racial Identity, and Multisystem Stress Response to Social Evaluative Threat Among African American Men and Women. Psychosom Med. 2017 Apr;79(3):293-305. doi: 10.1097/PSY.0000000000000406.

Reference Type BACKGROUND
PMID: 27806018 (View on PubMed)

Silk JS, Stroud LR, Siegle GJ, Dahl RE, Lee KH, Nelson EE. Peer acceptance and rejection through the eyes of youth: pupillary, eyetracking and ecological data from the Chatroom Interact task. Soc Cogn Affect Neurosci. 2012 Jan;7(1):93-105. doi: 10.1093/scan/nsr044. Epub 2011 Jul 20.

Reference Type BACKGROUND
PMID: 21775386 (View on PubMed)

Sladek MR, Castro SA, Doane LD. Ethnic-Racial discrimination experiences predict Latinx adolescents' physiological stress processes across college transition. Psychoneuroendocrinology. 2021 Jun;128:105212. doi: 10.1016/j.psyneuen.2021.105212. Epub 2021 Apr 1.

Reference Type BACKGROUND
PMID: 33933893 (View on PubMed)

Other Identifiers

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U5GMACGETKJ1

Identifier Type: -

Identifier Source: org_study_id

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