Angiopoietin and Adverse Outcomes in Cardiac Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-23

Study Completion Date

2027-04-30

Brief Summary

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Cardiac surgery and cardiopulmonary bypass can lead to systemic organ failure trough excess inflammation and endothelial injury. The angiopoietin family represented by angiopoietin 1 and 2 can reflect endothelial injury by a decrease in angiopoietin 1 and an increase in angiopoietin 2. The investigators hypothesized that angiopoietin dysregulation could reflect organ failure related to cardiac surgery.

The purpose of this project is to assess the association between angiopoietin dysregulation and adverse outcomes on cardiac surgery.

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Detailed Description

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Conditions

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Cardiac Surgery Acute Kidney Injury

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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cardiac surgery

Group Type EXPERIMENTAL

blood sample

Intervention Type OTHER

5 ml blood sample will be withdrawn at the surgery start and at the surgery end

Interventions

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blood sample

5 ml blood sample will be withdrawn at the surgery start and at the surgery end

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* adult patient scheduled for cardiac surgery under cardiopulmonary bypass

Exclusion Criteria

* patient less than 18 years old,
* redo surgery,
* urgent surgery,
* endocarditis,
* aortic root repair surgery
* aortic dissection
* heart beating surgery,
* heart transplantation

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No