Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study

NCT ID: NCT05810571

Last Updated: 2024-10-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-24

Study Completion Date

2027-01-03

Brief Summary

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patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continuous remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Detailed Description

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patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continious remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Conditions

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Renal Cell Carcinoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

DOUBLE

Participants Outcome Assessors
participant will not know which block applied, and the outcome assessor of the postoperative analgesia will not know

Study Groups

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patient controlled analgesia

this group of patients received no block, received only postoperative patient-controlled analgesia with morphine

Group Type PLACEBO_COMPARATOR

preoperative remifentanil consumption

Intervention Type PROCEDURE

continuous remifentanil infusion will applied for peroperative analgesia

postopeartive controlled anlagesia with morphine

Intervention Type PROCEDURE

postoperative morphine patient controlled analgesia will be applied for postoperative analgesia

erector spina plane block

this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine

Group Type ACTIVE_COMPARATOR

preoperative remifentanil consumption

Intervention Type PROCEDURE

continuous remifentanil infusion will applied for peroperative analgesia

postopeartive controlled anlagesia with morphine

Intervention Type PROCEDURE

postoperative morphine patient controlled analgesia will be applied for postoperative analgesia

quadratus lumborum block

this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine

Group Type ACTIVE_COMPARATOR

preoperative remifentanil consumption

Intervention Type PROCEDURE

continuous remifentanil infusion will applied for peroperative analgesia

postopeartive controlled anlagesia with morphine

Intervention Type PROCEDURE

postoperative morphine patient controlled analgesia will be applied for postoperative analgesia

Interventions

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preoperative remifentanil consumption

continuous remifentanil infusion will applied for peroperative analgesia

Intervention Type PROCEDURE

postopeartive controlled anlagesia with morphine

postoperative morphine patient controlled analgesia will be applied for postoperative analgesia

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* ASA 1-3
* open nephrectomy elective patients
* BMI\<35

Exclusion Criteria

* ASA 4-5-6
* Laparoscopic nephrectomy
* infection at the block side
* coagulation disorder
* BMI\>35
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kocaeli University

OTHER

Sponsor Role lead

Responsible Party

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Zehra Ipek ARSLAN

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Kocaeli University Medical Faculty

İzmit, , Turkey (Türkiye)

Site Status RECRUITING

Kocaeli University Medical Faculty

Kocaeli, , Turkey (Türkiye)

Site Status ACTIVE_NOT_RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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zehra ipek Arslan AYDIN, Professor

Role: CONTACT

00905325011339

Zehra ipek Arslan, Professor

Role: CONTACT

00905325011339

Facility Contacts

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Zehra İpek Arslan, Professor

Role: primary

00905325011339

Other Identifiers

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KAEK / 12bl.01

Identifier Type: -

Identifier Source: org_study_id

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