Retrospective and Prospective Cohort of Patients Entering the Multidisciplinary Management of Post-Covid Syndromes

NCT ID: NCT05805566

Last Updated: 2024-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

750 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-27

Study Completion Date

2029-04-30

Brief Summary

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SARS-CoV2 pneumonia has been a global public health emergency since 2020. The prevalence of the disease is particularly high with more than 500 million cases worldwide (7.5 million in France) since the emergence of the virus.

A substantial proportion of patients with SARS-Cov2 infection present persistent symptoms long after the acute infection. This is independent of the degree of severity of the SARS-Cov2 infection.

These symptoms can affect the quality of life and impede the return to work. While the majority of symptoms progress favourably with outpatient care, some persist and/or are particularly severe, justifying expert and multidisciplinary care.

This investigation aim to create a clinical database of patients with complex and/or severe post-CoviD and study blood markers what could predict the disease and orientate new ways of treatment.

Detailed Description

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Conditions

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Post-Covid Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Post-Covid Syndrome Patients

Blood collection

Intervention Type OTHER

Blood samples will be collected from the patient at baseline. This blood will be collected during the standard of care blood drawing in extra.

Interventions

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Blood collection

Blood samples will be collected from the patient at baseline. This blood will be collected during the standard of care blood drawing in extra.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

All patients who have joined the Epsilon care pathway since its opening in February 2022, i.e.:

* Patients with post-Covid syndrome referred to the Epsilon sector from the city medicine:
* Patient with documented SARS-Cov2 pneumonia
* With persistent and severe symptoms beyond 4 weeks or complex or disabling symptoms beyond 3 months
* Patient over 18 years old.

Post-hospital sector:

* Patient with documented SARS-Cov2 pneumonia
* Hospitalized for oxygen therapy (at least 48h)
* Not having a referring pulmonologist
* Not institutionalized
* With a life expectancy of more than 6 months.

Exclusion Criteria

* Patient refusing that this data to be used for research purposes (objection form).
* Patient with untreated comorbidities
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sébastien COURAUD, Pr

Role: PRINCIPAL_INVESTIGATOR

Department of Acute Pneumology and Thoracic Oncology, Hôpital Lyon Sud, Hospices Civils de Lyon

Locations

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Department of Acute Pneumology and Thoracic Oncology, Hôpital Lyon Sud, Hospices Civils de Lyon

Pierre-Bénite, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Sébastien COURAUD, Pr

Role: CONTACT

+33 (0)4 78 86 44 01

Julie DE BERMONT

Role: CONTACT

+33 (0)4 78 86 66 98

Facility Contacts

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Sébastien COURAUD, Pr

Role: primary

Other Identifiers

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69HCL22_1053

Identifier Type: -

Identifier Source: org_study_id

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