Study to Investigate Long-term Pulmonary and Extrapulmonary Effects of COVID-19

NCT ID: NCT04581135

Last Updated: 2023-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

620 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-01

Study Completion Date

2022-01-30

Brief Summary

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Prospective Observational Swiss Cohort Study to Investigate Long-term Pulmonary and Extrapulmonary Effects of COVID-19.

Detailed Description

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COVID-19 is a coronavirus induced viral pneumonia leading to Acute Respiratory Distress Syndrome. Previous coronavirus infections (SARS and MERS) led to pulmonary fibrosis in up to 30%. Prospective evaluation of lung abnormalities and pulmonary fibrosis after COVID-19 infection is crucial as novel treatments against lung fibrosis of different etiologies are available. No data on pulmonary longterm effects in COVID-19 survivors are currently available. The nation-wide Swiss COVID-19 lung group establishes a meticulously characterized prospective cohort study on pulmonary long-term sequela of patients living in Switzerland.

Conditions

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COVID-19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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COVID-19 Lung

COVID-19 survivors in Switzerland

COVID-19

Intervention Type OTHER

Research project in which biological material is sampled and health-related personal data are collected and used for further research. Coded data are used.

Interventions

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COVID-19

Research project in which biological material is sampled and health-related personal data are collected and used for further research. Coded data are used.

Intervention Type OTHER

Other Intervention Names

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Sampling biological material Collection of health-related personal data

Eligibility Criteria

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Inclusion Criteria

* Signed written informed consent.
* All adult patients with COVID-19 over 18 years.

Exclusion Criteria

* Severe mental or physical disability precluding informed consent or compliance with the protocol for prospective data collection.
* Pregnancy.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Insel Gruppe AG, University Hospital Bern

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Manuela Funke-Chambour, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Bern, Department of Pulmonary Medicine - Lead Center

Locations

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St. Claraspital AG - Department of Pulmonary Medicine

Basel, , Switzerland

Site Status

Universtiy Hospital Bern (Inselspital), Department of Pulmonary Medicine - Lead Center

Bern, , Switzerland

Site Status

University and Hospital of Fribourg

Fribourg, , Switzerland

Site Status

Hôpitaux Universitaires de Genève - Service de Pneumologie

Geneva, , Switzerland

Site Status

CHUV - Service de Pneumologie

Lausanne, , Switzerland

Site Status

Clinica Moncucco

Lugano, , Switzerland

Site Status

Kantonspital St. Gallen - Klinik für Pneumologie und Schlafmedizin Lungenzentrum

Sankt Gallen, , Switzerland

Site Status

Hôpital du Valais - Service de Pneumologie

Sion, , Switzerland

Site Status

Universitätsspital Zürich - Klinik für Pneumologie

Zurich, , Switzerland

Site Status

Countries

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Switzerland

References

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Abu Hussein N, Machahua C, Ruchti SC, Horn MP, Piquilloud L, Prella M, Geiser TK, von Garnier C, Funke-Chambour M. Circulating calprotectin levels four months after severe and non-severe COVID-19. BMC Infect Dis. 2023 Oct 3;23(1):650. doi: 10.1186/s12879-023-08653-7.

Reference Type DERIVED
PMID: 37789266 (View on PubMed)

Other Identifiers

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2020-00799

Identifier Type: -

Identifier Source: org_study_id

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