Efficacy of Coconut Oil With Peppermint Essential for Oral Hygiene Routine

NCT ID: NCT05803109

Last Updated: 2025-05-11

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-08-21
• Study Completion Date: 2025-01-01

Brief Summary

This randomized clinical trial will be conducted to investigate the efficacy of an innovative tooth cleaning agent extra virgin coconut oil with peppermint essential oil by oil pulling and toothbrushing with oil on reducing salivary Streptococcus mutans levels, tooth decay and plaque buildup versus on the counter toothpaste in high caries risk patients.

Detailed Description

Everyday use of dental health care products has increased. Therefore, there is a legitimately increased interest of healthcare clinicians and consumers in substances added to the toothpaste with the intention to improve their performance and potential benefits and risks that may arise from it. As there are harmful products in the toothpaste for instance: (Fluoride, Sodium Lauryl Sulphate (SLS), Sodium Saccharin and Triclosan which is assumed that it because local reaction includes oral mucosa irritation and desquamation (stomatitis, glossitis, gingivitis, buccal mucositis), while systemic ones are allergic and acute or chronic toxic reactions. Rational Harmful products in the toothpaste for instance: (Fluoride, Sodium Lauryl Sulphate (SLS), Sodium Saccharin and Triclosan which is assumed that it because local reaction includes oral mucosa irritation and desquamation (stomatitis, glossitis, gingivitis, buccal mucositis), while systemic ones are allergic and acute or chronic toxic reactions.

Conditions

Fluoride Adverse Reaction

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

virgin cold-pressed coconut oil with Peppermint essential oil

Patients will be instructed to use one packet of the coco pull healthy blend of organic oil (virgin cold pressed coconut oil with Peppermint essential oil)and swish the oil in the mouth and pull it between teeth for 5 minutes then spit out the oil and brush their teeth with the oil for 2 minutes; such a regimen will be repeated twice daily for three months.

Group Type: EXPERIMENTAL

AVIVA-PURE-CocoPull-Organic-made in USA

Intervention Type: OTHER

virgin cold pressed coconut oil with Peppermint essential oil

The fluoride toothpaste (Colgate Total,

Patients will be instructed to brush their teeth with the fluoride toothpaste (Colgat Total, 1450 ppm) for 2 minutes; such a regimen will be repeated two times daily for three months and use 10 ml of 0.12% chlorhexidine rinse for 1 min/day, 30 min after tooth brushing before going to bed.

Group Type: ACTIVE_COMPARATOR

AVIVA-PURE-CocoPull-Organic-made in USA

Intervention Type: OTHER

virgin cold pressed coconut oil with Peppermint essential oil

Interventions

AVIVA-PURE-CocoPull-Organic-made in USA

virgin cold pressed coconut oil with Peppermint essential oil

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients will be recruited in this study, will be medically free.
• Age range 20-50 years
• Patients with high caries risk assessment (0- 30% high caries risk) according to Cariogram - a multifactorial risk assessment model for dental caries.
• Non-Smoking patients
• Not under antibiotic therapy either at the time of the study or up to the last month before the start of the study.
• Male or Female patients
• Patients have brushing habits
• No Fixed orthodontic treatment
• No active or untreated caries
• Patients on non-cariogenic diet

Exclusion Criteria

• Patients with a compromised medical history.
• Patients with low caries risk assessment according to Cariogram - a multifactorial risk assessment model for dental caries.
• Patients with severe or active periodontal disease.
• Patients with a history of allergy to any of the drugs or chemicals will be used in the study.
• Patients on any antibiotics during the past month.
• Smoking patient
• Patients with very low saliva secretion xerostomia less than 0.5ml stimulated saliva /min score 3 according to Cariogram
• Pregnant female patient
• No brushing habits
• Fixed orthodontic treatment
• Active or untreated caries
• Patients on cariogenic diet

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Asmaa Mohamed Reda Ahmed Ali

Assistant lecture

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Faculty of Dentistry Cairo University

Cairo, Kasr El Ainy, Egypt

Countries

Egypt

Other Identifiers

CairoU 4 7 22

Identifier Type: -

Identifier Source: org_study_id