Evaluation of the Effectiveness of the Self-developed Pulmonary Lobar Ventilation Detector

NCT ID: NCT05799040

Last Updated: 2024-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-26

Study Completion Date

2024-12-31

Brief Summary

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The goal of observational study is to Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector.

Participants will use the self-developed pulmonary lobar ventilation detector and the imported Chartis detection system to evaluate the target pulmonary lobar collateral ventilation.

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Self-developed pulmonary lobar ventilation detector

Self-developed pulmonary lobar ventilation detector

Intervention Type DEVICE

The participants would evaluated by the self-developed pulmonary lobar ventilation detector.

imported Chartis detection system

Chartis detection system

Intervention Type DEVICE

The participants would evaluated by the Chartis detection system.

Interventions

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Self-developed pulmonary lobar ventilation detector

The participants would evaluated by the self-developed pulmonary lobar ventilation detector.

Intervention Type DEVICE

Chartis detection system

The participants would evaluated by the Chartis detection system.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with chronic obstructive pulmonary disease who meet the GOLD diagnostic criteria
* FEV1 ≤ 45% pred and FEV1/FVC\<70%
* TLC\>100% pred and RV\>175% pred
* CAT≥18
* \>50% of emphysema destruction
* Smoking prohibition\>6 months
* Sign the informed consent form

Exclusion Criteria

* PaCO2\>8.0 kPa, or PaO2\<6.0 kPa
* 6-minute walking test\<160m
* Obvious chronic bronchitis, bronchiectasis or other infectious lung diseases
* Three hospitalizations due to pulmonary infection in the past 12 months before the baseline assessment
* Previous lobectomy, LVRS or lung transplantation
* LVEF\<45% and or RVSP\>50mmHg
* Anticoagulant therapy that cannot be stopped before surgery
* The patient has obvious immune deficiency
* Participated in other lung drug studies within 30 days before this study
* Pulmonary nodules requiring intervention
* Any disease or condition that interferes with the completion of the initial or subsequent assessment
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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China-Japan Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Gang Hou

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Mingming Deng, MD

Role: CONTACT

86 18801336854

Facility Contacts

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Gang Hou, Professor

Role: primary

13840065481

Mingming Deng, Doctor

Role: backup

18801336854

Other Identifiers

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2022-NHLHCRF-LX-01-0202-3

Identifier Type: -

Identifier Source: org_study_id

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