Supporting Women With Breast Cancer to Practice DIBH at Home Before Radiation Therapy

NCT ID: NCT05791084

Last Updated: 2023-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-01

Study Completion Date

2029-03-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To examine the effect of a preparatory digital tool including a new instruction for deep inspiration breath hold (DIBH), before start of radiation therapy in women diagnosed with left sided breast cancer, compared with usual care.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The following questions will be posted:

* Are there any differences in levels of distress (primary outcome) between the control and intervention group at baseline and over time?
* Are there any differences in preparedness for RT (secondary outcomes) between the control and intervention group at baseline and over time?
* Are there any correlations between Health Literacy (HL) levels (secondary outcome) and levels of distress (primary outcome) in the control and intervention group?
* Are there any differences in objective clinical variables (chest mobility and respiratory movements and planned absorbed dose to the heart) between the control and intervention group before and after the intervention (baseline and at planning CT)?
* Which patterns of practice and use of the application (when, how, how often and for how long) can be discerned from the intervention group?
* Are there any correlations between different levels of practice and use of the digital tool and primary and secondary outcomes?
* How do patients in the different groups (control and intervention group) describe their experience of care and information process during RT with DIBH?
* Are there differences regarding health economic variables in terms of costs and health care usage (e.g., estimated time for planning and conducting computed tomography (CT), number of scheduled CT examinations) and patient effects (e.g. co-morbidities (heart related), sick leave, and quality-adjusted life year (QALYs) between patients in control- or interventions group?
* Are there any differences regarding effects on environmental aspects and costs in the different groups (control and intervention)?

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Health Literacy Distress, Emotional Preparedness Mobile Application

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

RCT with an intervention and control group
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

A=Control group who receives customary information prior to RT with DIBH.

Usual care and information before start of radiotherapy with DIBH.

Group Type NO_INTERVENTION

No interventions assigned to this group

B=Intervention group usual care and the DIBH-App to practice at-home before RT with DIBH.

Usual care and information and a mobile application with breathing instructions and a sensor to attach around the chest. To be able to train at home before radiotherapy with DIBH starts.

Group Type EXPERIMENTAL

mobile application with breathing instructions and a sensor to attach around the chest. To be able to train at home before radiotherapy with DIBH starts.

Intervention Type OTHER

The DIBH-App consists of 1) a mobile application that patients download to their own smart mobile phone, and 2) associated stretch-sensors that are attached around the chest and connected to the mobile phone via Bluetooth. Visually, the graphics is similar to the software used for DIBH in the RT department. Coaching takes place through instructional videos, text, and audio recordings (Image 2). The following information will be recorded and stored: date and time of practice, outcome of each session (including sensor data and calibration parameters), and user behavior within the application (such as screen visits, FAQ sections viewed, and key button presses).

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

mobile application with breathing instructions and a sensor to attach around the chest. To be able to train at home before radiotherapy with DIBH starts.

The DIBH-App consists of 1) a mobile application that patients download to their own smart mobile phone, and 2) associated stretch-sensors that are attached around the chest and connected to the mobile phone via Bluetooth. Visually, the graphics is similar to the software used for DIBH in the RT department. Coaching takes place through instructional videos, text, and audio recordings (Image 2). The following information will be recorded and stored: date and time of practice, outcome of each session (including sensor data and calibration parameters), and user behavior within the application (such as screen visits, FAQ sections viewed, and key button presses).

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients \> 18 years of age
* with a left-sided breast cancer diagnosis or DCIS
* who are to receive RT with DIBH technology
* with curative intention
* preparatory CT visit minimum 7 days to a maximum of 4 weeks
* able to speak and understand good enough Swedish to be able to assimilate content in the mobile app and answer surveys and interview questions
* have access to a smart mobile phone.

Exclusion Criteria

* patients receiving palliative RT or neoadjuvant chemotherap
* Planning CT starting \< 7 days
* people with some form of orthopedic, rheumatological or neurological injury or disease that limits the possibility of carrying out the intervention.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Jonkoping University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Maria Brovall

associated professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

maria Brovall, ass prof

Role: PRINCIPAL_INVESTIGATOR

Jonkoping University

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

maria Brovall, ass prof

Role: CONTACT

+46705501097

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2021-04031

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Breast Cancer Lung Late Effects
NCT02725840 COMPLETED
Ultrahypofractionation and Normal Tissue Toxicity
NCT05912231 ACTIVE_NOT_RECRUITING NA