Drug Administration From Enteral Nutrition Tube

NCT ID: NCT05790291

Last Updated: 2023-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

69 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-15

Study Completion Date

2022-06-15

Brief Summary

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Enteral nutrition protocols are applied in patients who do not have gastrointestinal dysfunction but in whom oral feeding is contraindicated. In these patients, where drug use is also necessary but alternative drug administration routes are not possible, drugs can be given to the patient through enteral nutrition tubes. However, there are studies reporting errors and complications during drug administration from the enteral nutrition tube. With the planned thesis study, it is aimed to develop an evidence-based checklist and to reduce the rate of errors and complications in drug administration through enteral feeding tube with this checklist.

Detailed Description

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Enteral nutrition protocols are applied in patients who do not have gastrointestinal dysfunction but in whom oral feeding is contraindicated. In these patients, where drug use is also necessary but alternative drug administration routes are not possible, drugs can be given to the patient through enteral nutrition tubes.

When adding drugs to parenteral nutrition admixtures or using concomitant drugs from the same catheter, it has become a general rule to check for drug incompatibility. The same level of care is not taken in drug administration from the enteral nutrition tube. There are studies reporting errors and complications in enteral drug administration in the literature Today, one of the most important parts of corporate culture in healthcare is patient safety. Patient safety is all of the measures taken by health institutions and employees in these institutions in order to prevent the harm that health care services may cause to individuals. The main goal here is; It is the establishment of a system that will protect the patient from possible harm and eliminate the possibility of error due to errors that will prevent the occurrence of errors during care delivery.

The checklists used in recent years are also an evidence-based practice list and have become one of the effective methods used to prevent errors and reduce complications. A checklist standardizes the process, streamlines maintenance delivery, and improves performance to ensure all actions are covered. The checklist allows cross-checking what was done and in what order. These reassurances are important in situations where time is short and distractions.

With this study, it is aimed to develop an evidence-based checklist and to reduce the rate of errors and complications in drug administration through enteral feeding tube with this checklist.

Conditions

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Intensive Care

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

randomized control
Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
First, the participants were blinded. Participants were randomized after the pretest and divided into two groups. No explanation was given to the participants about how many groups there were and which group they belonged to.

Second, the observer was blinded. Video recording was taken by the researcher during the administration in calculating the error rates.

The video recordings were watched one by one by an assistant researcher who did not know the groups, and the administration steps were marked on the observation form as true/false.

Third, the statistician was blinded.

Study Groups

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checklist

checklist

Group Type EXPERIMENTAL

Checklist

Intervention Type OTHER

the experimental group will practice using the checklist

no intervention

no intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Checklist

the experimental group will practice using the checklist

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Being an intensive care nurse
* Have experience in administering enteral medication
* Administering enteral medication to an adult patient
* Agree to participate in the research

Exclusion Criteria

* Administering enteral medication to a patient with fluid restriction
* Change of position
* Wanting to leave research
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Emel Külekçi

OTHER

Sponsor Role lead

Responsible Party

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Emel Külekçi

Lecturer

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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EMEL KÜLEKCİ

Role: PRINCIPAL_INVESTIGATOR

PhD student

Locations

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Sağlık Bilimleri Üniversitesi

Ankara, Keçiören, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Demirkan K, Ekincioğlu AB. Enteral Beslenme Tüpünden İlaç Uygulanmasında İlaç Dozaj Şekillerinin Önemi. Journal of the Turkish Society of Intensive Care/Türk Yogun Bakim Dernegi Dergisi. 2016;14(1):1-8.

Reference Type BACKGROUND

Ekincioglu AB, Demirkan K. Clinical nutrition and drug interactions. Ulus Cerrahi Derg. 2013 Nov 14;29(4):177-86. doi: 10.5152/UCD.2013.112013. eCollection 2013.

Reference Type BACKGROUND
PMID: 25931873 (View on PubMed)

Abu Hdaib N, Albsoul-Younes A, Wazaify M. Oral medications administration through enteral feeding tube: Clinical pharmacist-led educational intervention to improve knowledge of Intensive care units' nurses at Jordan University Hospital. Saudi Pharm J. 2021 Feb;29(2):134-142. doi: 10.1016/j.jsps.2020.12.015. Epub 2021 Jan 7.

Reference Type BACKGROUND
PMID: 33679176 (View on PubMed)

Sari D, Kadifeli D, Akbiyik A, Taskiran N. Intensive care unit nurses' knowledge of medication administration via enteral tubes. Nurs Crit Care. 2018 May;23(3):141-146. doi: 10.1111/nicc.12335. Epub 2018 Feb 8.

Reference Type BACKGROUND
PMID: 29424127 (View on PubMed)

Çelik S, Demiray Y, Tuğrul A, Köymen H, Coşkun Y, Doğru Ö, et al. Yoğun bakım hemşirelerinin enteral tüp aracılığıyla ilaç uygulamalarının değerlendirilmesi. Çağdaş Tıp Dergisi. 2014;4(1):18-25.

Reference Type BACKGROUND

Emami S, Hamishehkar H, Mahmoodpoor A, Mashayekhi S, Asgharian P. Errors of oral medication administration in a patient with enteral feeding tube. J Res Pharm Pract. 2012 Jul;1(1):37-40. doi: 10.4103/2279-042X.99677.

Reference Type BACKGROUND
PMID: 24991587 (View on PubMed)

Özkan D, Yavuz Van Giersbergen M. Güvenli Cerrahi Kontrol Listesi Konusunda Ameliyathane Ekibinin Düşüncelerinin İncelenmesi. Turkiye Klinikleri J Surg Nurs-Special Topics Türkiye Klinikleri Cerrahi Hastalıkları Hemşireliği-Güvenli Cerrahi Uygulamaları Özel Sayısı. 2016;2(3):22-8

Reference Type BACKGROUND

Winters BD, Gurses AP, Lehmann H, Sexton JB, Rampersad CJ, Pronovost PJ. Clinical review: checklists - translating evidence into practice. Crit Care. 2009;13(6):210. doi: 10.1186/cc7792. Epub 2009 Dec 31.

Reference Type BACKGROUND
PMID: 20064195 (View on PubMed)

Bankhead R, Boullata J, Brantley S, Corkins M, Guenter P, Krenitsky J, Lyman B, Metheny NA, Mueller C, Robbins S, Wessel J; A.S.P.E.N. Board of Directors. Enteral nutrition practice recommendations. JPEN J Parenter Enteral Nutr. 2009 Mar-Apr;33(2):122-67. doi: 10.1177/0148607108330314. Epub 2009 Jan 26. No abstract available.

Reference Type BACKGROUND
PMID: 19171692 (View on PubMed)

Boullata JI, Carrera AL, Harvey L, Escuro AA, Hudson L, Mays A, McGinnis C, Wessel JJ, Bajpai S, Beebe ML, Kinn TJ, Klang MG, Lord L, Martin K, Pompeii-Wolfe C, Sullivan J, Wood A, Malone A, Guenter P; ASPEN Safe Practices for Enteral Nutrition Therapy Task Force, American Society for Parenteral and Enteral Nutrition. ASPEN Safe Practices for Enteral Nutrition Therapy [Formula: see text]. JPEN J Parenter Enteral Nutr. 2017 Jan;41(1):15-103. doi: 10.1177/0148607116673053. Epub 2016 Nov 5.

Reference Type BACKGROUND
PMID: 27815525 (View on PubMed)

Bischoff SC, Austin P, Boeykens K, Chourdakis M, Cuerda C, Jonkers-Schuitema C, Lichota M, Nyulasi I, Schneider SM, Stanga Z, Pironi L. ESPEN guideline on home enteral nutrition. Clin Nutr. 2020 Jan;39(1):5-22. doi: 10.1016/j.clnu.2019.04.022. Epub 2019 May 30.

Reference Type BACKGROUND
PMID: 31255350 (View on PubMed)

Provided Documents

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Document Type: Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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2021/29

Identifier Type: -

Identifier Source: org_study_id

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