Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals

NCT ID: NCT05780697

Last Updated: 2023-03-22

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-03-31
• Study Completion Date: 2025-03-31

Brief Summary

Detect short term results of pediatric septic hip arthritis and its risk factors

Detailed Description

Septic arthritis of the hip is a true orthopedic emergency(1). In developed countries, the incidence of acute bacterial septic arthritis is estimated to be 4 to 10 per 100,000 children (2).It is caused by many microorganisms. Staph aureus is most common in children over 2 years of age . Staph aureus is gram-positive cocci in clusters and most common in nosocomial infections of neonates(3-4).Group B streptococcus is most common in neonates with community-acquired infection and exposed during transvaginal delivery(5).Neisseria gonorrhoeae is gram-negative diplococci and most common in adolescents.when the causative Organism is Neisseria gonorrhoeae ,patients usually have a preceding migratory polyarthralgia,multiple joint involvement and small red papules(6-7).Group A beta-hemolytic streptococcus is most common organism following varicella infection.HACEK organisms (Haeophilus,Actinobacillus,Cardiobacterium,Eikenella,and Kingella fastidious) are less common causative organisms(8-9).Early diagnosis and accurate treatment is key in avoiding complications such as joint destruction,joint dislocation , ankylosis, growth arrest or spread of infection leading to osteomyelitis , pelvic abscess or nerve lesions.. Treatment is started without delay after synovial fluid and blood samples have been obtained. The classical presentation of septic hip arthritis in children is a combination of a painful hip joint with limited range of motion, fever, malaise and inability to bear weight on the affected limb. Misdiagnosis or inappropriate treatment of acute septic arthritis of the hip in children can result in devastating damage of the joint and possible lifelong disability. Open arthrotomy , drainage and thorough irrigation of the joint is considered the standard treatment for septic arthritis of the hip.Empiric antibiotic treatment primarily targets S. aureus and takes into account its resistance to antibiotics(10-11). So,we want to detect short term results of pediatric septic hip arthritis at Assiut University Hospitals

Conditions

Septic Arthritis

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Children presented with septic hip arthritis in Assiut University Hospitals

Surgery of Drainage of pus in septic hip arthritis

Group Type: EXPERIMENTAL

Surgery of Drainage of septic hip arthritis

Intervention Type: PROCEDURE

Surgery for septic hip arthritis by anterior or lateral approach and inspection of femoral head

Interventions

Surgery of Drainage of septic hip arthritis

Surgery for septic hip arthritis by anterior or lateral approach and inspection of femoral head

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Children younger than 14 years old presented with septic hip arthritis only or by bilateral septic hip arthritis in Assiut University Hospitals

Exclusion Criteria

• 1-patients with Tuberculous arthritis 2-patients whose parents refuse to participate in the study

• Minimum Eligible Age: 1 Day
• Maximum Eligible Age: 14 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Beshoy Elkess Ibram

Resident Dr

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Beshoy Elkes Abram, Resident Dr

Role: CONTACT

Beshoelghalban_2010@yahoo.com

01284144493

References

Fabry G, Meire E. Septic arthritis of the hip in children: poor results after late and inadequate treatment. J Pediatr Orthop. 1983 Sep;3(4):461-6. doi: 10.1097/01241398-198309000-00008.

Reference Type: BACKGROUND

PMID: 6630490 (View on PubMed)

Ilharreborde B. Sequelae of pediatric osteoarticular infection. Orthop Traumatol Surg Res. 2015 Feb;101(1 Suppl):S129-37. doi: 10.1016/j.otsr.2014.07.029. Epub 2014 Dec 29.

Reference Type: BACKGROUND

PMID: 25553604 (View on PubMed)

Other Identifiers

Pediatric Septic Hip arthritis

Identifier Type: -

Identifier Source: org_study_id