Effect Of Calcitriol On Neutrophil To Lymphocytes Ratio And High Sensitivity C-Reactive Protein Covid-19 Patients

NCT ID: NCT05765617

Last Updated: 2023-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-01

Study Completion Date

2021-09-30

Brief Summary

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This research is a study that compares the administration of calcitriol with the outcomes of COVID-19 patients

Detailed Description

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This research was an observational analytic cohort retrospective study in which the subjects were moderate degree COVID-19 inpatients in Sebelas Maret University Hospital divided into two groups. The control group received standard therapy, while the treatment group received calcitriol 2x400 iu per day.

Conditions

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COVID-19

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This research was an observational analytic cohort retrospective study in which the subjects were moderate degree COVID-19 inpatients in Sebelas Maret University Hospital divided into two groups. The control group received standard therapy, while the treatment group received calcitriol 2x400 iu per day.
Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
This study used calcitriol and a placebo, which were similar in shape; researchers and patients did not know who was getting the drug or placebo.

Study Groups

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Control

Placebo 2x1 per day

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

Placebo give 2x1 per day for five day

Calcitriol

the treatment group received calcitriol 2x400 iu per day for 5 day

Group Type EXPERIMENTAL

Calcitriol

Intervention Type DRUG

The treatment group received calcitriol 2x400 iu per day for five days. Calcitriol uses Oscal, obtained from Kalbe Pharma

Interventions

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Calcitriol

The treatment group received calcitriol 2x400 iu per day for five days. Calcitriol uses Oscal, obtained from Kalbe Pharma

Intervention Type DRUG

Placebo

Placebo give 2x1 per day for five day

Intervention Type OTHER

Other Intervention Names

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Oscal

Eligibility Criteria

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Inclusion Criteria

* COVID-19 patients, hospitalized patients, and patients aged 18-60 years

Exclusion Criteria

* pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitas Sebelas Maret

OTHER

Sponsor Role lead

Responsible Party

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Nurhasan Agung Prabowo

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nurhasan Agung Prabowo, MD

Role: PRINCIPAL_INVESTIGATOR

Universitas Sebelas Maret

Locations

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Universitas Sebelas Maret Hospital

Sukoharjo, Central Java, Indonesia

Site Status

Countries

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Indonesia

Other Identifiers

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NAP03

Identifier Type: -

Identifier Source: org_study_id

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