The Influence of Endurance Sports Activity on the Oral Microbiota of Young Adults.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-17

Study Completion Date

2026-03-15

Brief Summary

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The oral cavity is an easily accessible anatomical site that accurately reflects the health of the individual. The mouth is considered an early indicator of biological aging, leading to the identification of oral biomarkers predictive of future alterations. Current data show that the oral health of high level athletes is globally altered with an increase in cariogenic indexes, an increased incidence of periodontitis, dental trauma and dry mouth syndromes. Few studies have focused on the oral microbiota compared to mouthguards used in rugby or boxing which seem to induce dysbiosis, a recent study shows an effect of ketogenic diet on bacterial changes in the mouth of endurance athletes. This project focuses on the impact of intensive sport practice on oral health and the identification of oral biomarkers associated with physical activity. The objective of this study is to investigate the impact of the amount of endurance sport practice on oral microbiota and oral health in young adults. the hypothesis is that a sedentary lifestyle and high-level sport induce depletion and/or changes in the oral microbiota compared to regular physical activity.

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Detailed Description

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Conditions

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Microbial Colonization

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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sedentary

Participant does not meet WHO's recommendations with the physical activity

Group Type OTHER

salivar and gum sampling

Intervention Type OTHER

Saliva will then be collected by salivary spit and a mucosal smear will be taken using a swab passed at the junction of the tooth and the gum

OMS recommandations

Participant does not meet WHO's recommendations (2.5-5 hours per week of moderate physical activity OR 1.25-2.5 hours per week of vigorous physical activity);

Group Type OTHER

salivar and gum sampling

Intervention Type OTHER

Saliva will then be collected by salivary spit and a mucosal smear will be taken using a swab passed at the junction of the tooth and the gum

More than the OMS recommandations

Participant is practicing physical activity more than the WHO recommendations

Group Type OTHER

salivar and gum sampling

Intervention Type OTHER

Saliva will then be collected by salivary spit and a mucosal smear will be taken using a swab passed at the junction of the tooth and the gum

Interventions

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salivar and gum sampling

Saliva will then be collected by salivary spit and a mucosal smear will be taken using a swab passed at the junction of the tooth and the gum

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Be between 18 and 30 years old
* If practicing sports, it must be an endurance sport as main activity (cycling or running)

Exclusion Criteria

* Practice more than 3 hours of swimming per week
* Have taken anti-inflammatory drugs, less than 48 hours before the study
* Have taken antibiotics and/or probiotics, less than 3 weeks before the study

Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes