Oral Health, Microbial Burden and COVID-19

NCT ID: NCT04668911

Last Updated: 2021-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-12-13

Study Completion Date

2021-12-12

Brief Summary

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An observational study of patients with COVID-19 confirmed cases (with various degrees of severity) and controls.

Oral and nasal swabs will be taken from 150 patients (50 with mild form and 50 with severe form of COVID-19 with or without mechanical ventilation, 50 healthy controls).

Detailed Description

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Conditions

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Covid19 Periodontitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Controls tested PCR (-) for COVID-19

Swab

Intervention Type OTHER

PCR test for SARS-CoV2, oral and nasal swab

Tested PCR (+) for COVID-19, Mild - not admitted to the hospital

Swab

Intervention Type OTHER

PCR test for SARS-CoV2, oral and nasal swab

Tested PCR (+) for COVID-19, Severe - admitted to ICU (Intensive Care Unit)

Swab

Intervention Type OTHER

PCR test for SARS-CoV2, oral and nasal swab

Interventions

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Swab

PCR test for SARS-CoV2, oral and nasal swab

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Must provide written informed consent
2. Subjects have to be tested (PCR) positive or negative for SARS-CoV2 infection
3. Must be able to provide oral and nasal swabbing within 48 hours of polymerise chain reaction (PCR) test results

Exclusion Criteria

a. Under the age of 18 years old
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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DermBiont, Inc.

INDUSTRY

Sponsor Role collaborator

University College London Hospitals

OTHER

Sponsor Role collaborator

The Whittington Hospital NHS Trust

OTHER_GOV

Sponsor Role collaborator

Eastman Dental Insitute and Hospital

OTHER

Sponsor Role lead

Responsible Party

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Prof Francesco D'Aiuto

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University College Hospital (UCH), UCL Eastman Dental Institute

London, , United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Jeanie Suvan

Role: CONTACT

+442034561108

Facility Contacts

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Francesco D'Aiuto, DMD, PhD, MClinDent

Role: primary

Other Identifiers

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283766

Identifier Type: OTHER

Identifier Source: secondary_id

EDGE 132868

Identifier Type: -

Identifier Source: org_study_id

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