COVID-19: Nasal and Salivary Detection of the SARS-CoV-2 Virus After Antiviral Mouthrinses
NCT ID: NCT04352959
Last Updated: 2021-02-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
176 participants
INTERVENTIONAL
2020-04-27
2020-12-11
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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mouth rinse with antiviral
mouthrinse with bêta-cyclodextrin and citrox
3 daily mouthrinses for 7 days
mouth rinse without antiviral
mouthrinse without bêta-cyclodextrin and citrox
3 daily mouthrinses for 7 days
Interventions
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mouthrinse with bêta-cyclodextrin and citrox
3 daily mouthrinses for 7 days
mouthrinse without bêta-cyclodextrin and citrox
3 daily mouthrinses for 7 days
Eligibility Criteria
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Inclusion Criteria
* Clinical signs started less than 8 days ago.
* Virological confirmation
* Understanding and acceptance of the trial.
* Written agreement to participate in the trial
Exclusion Criteria
* Breastfeeding
* Inability to comply with protocol
* Lack of written agreement
18 Years
85 Years
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Claude Bernard University
OTHER
Responsible Party
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Carrouel Florence
Associate professor
Principal Investigators
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Florence Carrouel, Dr
Role: STUDY_DIRECTOR
University Claude Bernard Lyon 1
Locations
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Clinic of the Protestant Infirmary in Lyon
Caluire-et-Cuire, , France
Hospital Center Emile Roux
Le Puy-en-Velay, , France
Hospital Center Saint Luc Saint Joseph
Lyon, , France
Intercommunal Hospital Center of Mont de Marsan
Mont-de-Marsan, , France
Countries
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References
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Carrouel F, Conte MP, Fisher J, Goncalves LS, Dussart C, Llodra JC, Bourgeois D. COVID-19: A Recommendation to Examine the Effect of Mouthrinses with beta-Cyclodextrin Combined with Citrox in Preventing Infection and Progression. J Clin Med. 2020 Apr 15;9(4):1126. doi: 10.3390/jcm9041126.
Carrouel F, Goncalves LS, Conte MP, Campus G, Fisher J, Fraticelli L, Gadea-Deschamps E, Ottolenghi L, Bourgeois D. Antiviral Activity of Reagents in Mouth Rinses against SARS-CoV-2. J Dent Res. 2021 Feb;100(2):124-132. doi: 10.1177/0022034520967933. Epub 2020 Oct 22.
Carrouel F, Viennot S, Valette M, Cohen JM, Dussart C, Bourgeois D. Salivary and Nasal Detection of the SARS-CoV-2 Virus After Antiviral Mouthrinses (BBCovid): A structured summary of a study protocol for a randomised controlled trial. Trials. 2020 Nov 2;21(1):906. doi: 10.1186/s13063-020-04846-6.
Burton MJ, Clarkson JE, Goulao B, Glenny AM, McBain AJ, Schilder AG, Webster KE, Worthington HV. Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed COVID-19 infection to improve patient outcomes and to protect healthcare workers treating them. Cochrane Database Syst Rev. 2020 Sep 16;9(9):CD013627. doi: 10.1002/14651858.CD013627.pub2.
Other Identifiers
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BBCovid
Identifier Type: -
Identifier Source: org_study_id
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