Analysis of Oxidative Stress Biomarkers and Their Determinants in ART-experienced PLWH

NCT ID: NCT05760495

Last Updated: 2023-03-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

543 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-02

Study Completion Date

2023-05-10

Brief Summary

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The project aims to assess the level of oxidative stress biomarkers in HIV patients on effective antiretroviral treatment in correlation with other therapeutic, clinical, and viro- immunological parameters. The analysis aims to better characterize the patient on treatment through an innovative approach based on two specific tests for complementary assessment of total oxidant and anti-oxidant plasma capacity.

Detailed Description

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Conditions

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HIV Infections

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Study Groups

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Single arm

ART-experienced PLWH

blood sampling

Intervention Type OTHER

Blood sampling for evaluation of oxidative stress markers

Interventions

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blood sampling

Blood sampling for evaluation of oxidative stress markers

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ART-treated PLWH
* HIV-1 RNA\< 50 copies/mL
* Stable ART therapy (at least 48 weeks)
* Signature of informed consent for study participation

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Francesca Lombardi

Roma, RM, Italy

Site Status RECRUITING

Countries

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Italy

Facility Contacts

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Francesca Lombardi, PhD

Role: primary

003930155366

Other Identifiers

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4477

Identifier Type: -

Identifier Source: org_study_id

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