Low Grade Serous Ovarian Carcinoma and Uterine Involvement : Should Hysterectomy be the Rule

NCT ID: NCT05741554

Last Updated: 2023-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

28 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-01

Study Completion Date

2022-10-10

Brief Summary

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Investigators studied a population of 28 low grade serous ovarian carcinoma treated in Hospices civils de Lyon between 2000 and 2022. The primary objective is to determinate the rate of myometrial involvement by the cancer at pathology examination. Then, investigators compared patients with or without myometrial involvement : survival parameters, predictive factors of myometrial involvement (age, CA 125 level, surgery characteristics, pathology characteristics).

Detailed Description

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Conditions

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Serous Ovarian Carcinoma Low Grade Serous Ovarian Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Myometrial involvement

Myometrial involvement by cancer metastasis after pathology examination

Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.

Intervention Type OTHER

Presence of uterine myometrial metastasis at pathology examination after cytoreductive surgery

No myometrial involvement

Absence of myometrial involvement by cancer metastasis after pathology examination

Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.

Intervention Type OTHER

Presence of uterine myometrial metastasis at pathology examination after cytoreductive surgery

Interventions

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Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.

Presence of uterine myometrial metastasis at pathology examination after cytoreductive surgery

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18 years old or more
* low grade serous ovarian cancer (MDACC classification)
* Grade 1 serous ovarian carcinoma (Silverberg classification)

Exclusion Criteria

* no sufficient data available
* grade 2 and 3 serous ovarian carcinoma
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hospices civils de Lyon

Lyon, , France

Site Status

Countries

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France

Other Identifiers

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69HCL23_0175

Identifier Type: OTHER

Identifier Source: secondary_id

22-5035

Identifier Type: -

Identifier Source: org_study_id

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