Comparison of Four Intensive Care Scores in Prediction of VA-ECMO Survival.

NCT ID: NCT05730881

Last Updated: 2023-09-28

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-03-30
• Study Completion Date: 2023-11-30

Brief Summary

VA-ECMO is increasingly utilized in the setting of cardiogenic shock or cardiac arrest to restore hemodynamic stability and end organ function. VA-ECMO serves as a short-term ventricular assist device that can be rapidly placed at the bedside in the emergency room, intensive care unit, cardiac catheterization suite, or operating room. A bridge to decision approach allows for the assessment of neurologic status, renal and hepatic function, and subsequent recovery of cardiac function. Despite its life-saving potential, VA-ECMO is fraught with complications including vascular complications from cannulation. In addition, neurologic injury, renal failure, liver failure, and sepsis are all well described sequelae of the post-cardiogenic shock or cardiac arrest VA-ECMO patient. For these reasons, identifying early prognostic indicators and developing a score with regard to the outcome of this special patient population is of high interest. The proposed study aims to analyze 4 ICU scores/Survival prediction models [APACHE-II (acute physiology and chronic health evaluation II), SAVE (Survival after VA ECMO) , SOFA (sequential organ failure assessment )and CASUS (Cardiac Surgery Score)] and evaluate their performance in predicting survival after VA ECMO insertion. This will be a clinical retrospective study which will be conducted in the Cardiothoracic Intensive Care unit (CTICU) in the Department of Cardiothoracic Surgery, Heart Hospital, Doha. Patients admitted to the CTICU after institution of VA ECMO in the period between 1st January 2015 to 31st October 2022 will be screened retrospectively. Patients who stay for at least 12 hours in the CTICU would be eligible for inclusion in the study. All charts of patients who were admitted to CTICU after institution of VA ECMO during the afore mentioned period will be included in the review. All the risk scores would be calculated separately for all the enrolled patients and then subjected to statistical analysis to determine predictive accuracy for survival.

Conditions

Cardiogenic Shock; Extracorporeal Membrane Oxygenation Complication

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Interventions

ECMO

VA-ECMO is a life support measures, we need to estimate the survival by different techniques to allocate therapeutic interventions properly

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Age more than18 years old.
• Patients undergoing institution of VA ECMO

Exclusion Criteria

• Patients staying < 12 hours in the ICU

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hamad Medical Corporation

INDUSTRY

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Suraj Sudarsanan, Md

Role: PRINCIPAL_INVESTIGATOR

Hamad medical coproation

Locations

Hamad medical corporation

Doha, DA, Qatar

Site Status: RECRUITING

Countries

Qatar

Central Contacts

Suraj Sudarsanan, MD

Role: CONTACT

Sudarsanan@hamad.qa

44395897

Praveen Sivadasan, MD

Role: CONTACT

drpraveencs@gmail.com

Facility Contacts

Suraj Sudarsanan, MD

Role: primary

ssudarsanan@hamad.qa

Other Identifiers

MRC-01-22-701

Identifier Type: -

Identifier Source: org_study_id