Anti-Müllerian Hormone and Embryo Aneuploidy

NCT ID: NCT05723016

Last Updated: 2023-02-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2022-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this observational study is to determine is there an association between the rates of aneuploidy and the different ranges of serum Antimullerian hormone (AMH) levels.

Retrospective, single-centre study of patients undergoing IVF and preimplantation genetic testing with aneuploidy at the blastocyst stage between January 2018 and December 2022.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Infertility Aneuploidy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

AMH < 0.5 ng/ml

preimplantation genetic test for aneuploidies (PGT-a)

Intervention Type OTHER

preimplantation genetic test for embryo aneuploidies after IVF

AMH 0.5-0.99 ng/ml

preimplantation genetic test for aneuploidies (PGT-a)

Intervention Type OTHER

preimplantation genetic test for embryo aneuploidies after IVF

AMH 1.0-1.49 ng/ml

preimplantation genetic test for aneuploidies (PGT-a)

Intervention Type OTHER

preimplantation genetic test for embryo aneuploidies after IVF

AMH 1.5-1.99 ng/ml

preimplantation genetic test for aneuploidies (PGT-a)

Intervention Type OTHER

preimplantation genetic test for embryo aneuploidies after IVF

AMH 2.0-4.99 ng/ml

preimplantation genetic test for aneuploidies (PGT-a)

Intervention Type OTHER

preimplantation genetic test for embryo aneuploidies after IVF

AMH > 5.0 ng/ml

preimplantation genetic test for aneuploidies (PGT-a)

Intervention Type OTHER

preimplantation genetic test for embryo aneuploidies after IVF

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

preimplantation genetic test for aneuploidies (PGT-a)

preimplantation genetic test for embryo aneuploidies after IVF

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* All started cycles planned to be followed by preimplantation genetic testing for aneuploidies (PGT-A). PGT-A is proposed to the couples for the following reasons: advanced maternal age, recurrent miscarriage, repeated implantation failure or severe male infertility factor; it is also offered to all patients with a good prognosis who desired information regarding the ploidy status of their embryos.

Exclusion Criteria

* Data from oocyte donation cycles
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Clinica de la Mujer Medicina Reproductiva, Chile

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Jose Antonio Moreno

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Clinica de la Mujer Medicina Reproductiva

Viña del Mar, Región de Valparaíso, Chile

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Chile

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

AMH 2023

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.