Effects of Different Ventilatory Strategy on Intraoperative Atelectasis During Bronchoscopy Under General Anesthesia.

NCT ID: NCT05720845

Last Updated: 2023-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-02-08

Study Completion Date

2025-03-18

Brief Summary

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This trial compares two different types of ventilation for the prevention of partial or complete collapsed lung (atelectasis) in patients undergoing interventional pulmonology procedures under general anesthesia. Ventilatory strategy to prevent reduce the intra-procedural development of atelectasis during interventional pulmonology procedures under general anesthesia.

Detailed Description

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Conditions

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Lung Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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conventional mechanical ventilation

Conventional mechanical ventilation for General Anesthesia

Group Type ACTIVE_COMPARATOR

conventional mechanical ventilation

Intervention Type PROCEDURE

Conventional mechanical ventilation for General Anesthesia.

VESPA

ventilatory strategy to prevent atelectasis for General Anesthesia

Group Type EXPERIMENTAL

VESPA

Intervention Type PROCEDURE

Using Ventilatory strategy of prevent atelectasis for General Anesthesia.

Interventions

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VESPA

Using Ventilatory strategy of prevent atelectasis for General Anesthesia.

Intervention Type PROCEDURE

conventional mechanical ventilation

Conventional mechanical ventilation for General Anesthesia.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Adult patients undergoing interventional pulmonology procedures with radial probe endobronchial ultrasound (RP-EBUS) for peripheral lung lesions
* Recent (\< 4 weeks) chest computed tomography (CT) performed prior to the bronchoscopy

Exclusion Criteria

* Patients with baseline lung consolidation, interstitial changes or lung masses (\> 3 cm in diameter) in dependent areas of the lung (right/left \[R/L\] B6, 9, or 10 bronchial segments) as seen on most recent CT
* History of primary or secondary spontaneous pneumothorax
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Guangzhou Institute of Respiratory Disease

OTHER

Sponsor Role lead

Responsible Party

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ShiYue Li

Director of Department of Respiratory Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Site Status

Countries

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China

Other Identifiers

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20230111

Identifier Type: -

Identifier Source: org_study_id

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