ARTIFICIAL INTELLIGENCE IN REPRODUCTIVE MEDICINE

NCT ID: NCT05699850

Last Updated: 2023-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-11-01

Study Completion Date

2023-04-01

Brief Summary

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Many studies have been published investigating the use of AI as an unbiased, automated approach to embryo assessment. This review will summarize the recent AI advancements in the IVF field. Hopefully, that incorporating AI technology into the IVF clinics may be the next frontier in the journey towards personalised reproductive medicine and improved fertility outcomes for patients.

Detailed Description

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ARTIFICIAL INTELLIGENCE (AI) APPLICATIONS IN REPRODUCTIVE MEDICINE

Kamaleldin Abdullah Rageh, M.D. (1).

Mohammad Atef Behery, M.D. (2)

Elsayed Ali Farag, M.D. (1)

1 -Department of Obstetrics and Gynecology, Faculty of medicine, Al-Azhar University, Cairo, Egypt.

2-International Islamic Center for Population Studies and Research, Al-Azhar University, Cairo, Egypt.

Abstract:

In spite of improved almost all aspects of IVF: ovarian stimulation, embryo culture and transfer, the pregnancy rates still not satisfactory. Studies confirm that up to 50% of the performed IVF cycles fail and there may be no direct explanation for this.

And it's worthy to mention that accurately predicting the outcome of an IVF cycle has yet to be achieved. One reason for this is the method of selecting an embryo for transfer. Morphological assessment of embryos is the traditional method of evaluating embryo quality and selecting which embryo to transfer. However, this subjective method of assessing embryos leads to inter- and intra-observer variability, resulting in less than optimal IVF success rates. Although time-lapse incubators and preimplantation genetic testing for aneuploidy have been introduced to help increase the chances of live birth, the outcomes remain less than ideal.

Currently, infertility treatments exert a lot of financial and emotional stress, especially in patients with previously failed IVF treatments, where there is no clear cause to be identified is a common, heartbreaking endpoint when the emotional, financial and physical burden of the treatment escalate to continue finding answers, but AI systems might help solve the dilemma by picking the best viable embryos that humans can't do. AI technologies have excellent potential to help the infertility field to soar over its current narrow focus on individual embryos and detect new patterns hidden in the patient data for overcoming the prevailing infertility cases.

The embryo selection is the most critical factor for the success of IVF. However, there is no single definitive criterion that can predict the success of an embryo. Rather, embryo selection is based on a variety of factors, making it is difficult to predict the probability of a successful pregnancy for each patient and to fully understand the cause of each failure. So, Utilization of artificial intelligence (AI) may support the clinicians in filling this knowledge gap, thereby being leveraged in the embryology laboratory to help improve IVF outcomes.

Conditions

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ARTIFICIAL INTELLIGENCE (AI) APPLICATIONS IN REPRODUCTIVE MEDICINE

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Interventions

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ARTIFICIAL INTELLIGENCE (AI)

ARTIFICIAL INTELLIGENCE (AI) APPLICATIONS IN REPRODUCTIVE MEDICINE

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* fertility related

Exclusion Criteria

* fertile people
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Al-Azhar University

OTHER

Sponsor Role collaborator

Al Baraka Fertility Hospital

OTHER

Sponsor Role lead

Responsible Party

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Dr. Kamal Rageh, MD

consultant Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Al-Azhar university

Cairo, , Egypt

Site Status RECRUITING

Kamal Eldin Abdalla Rageh

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Facility Contacts

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Dr. Mohammed Atef, M.D.

Role: primary

00201006206040

Kamal Eldin A Rageh

Role: primary

0097333153871

Other Identifiers

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Kamal-AI

Identifier Type: -

Identifier Source: org_study_id

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