Assessment of Endometrial Pattern and Sub-endometrial Vascularity in ICSI Outcome

NCT ID: NCT03683771

Last Updated: 2019-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-09-28

Study Completion Date

2019-02-20

Brief Summary

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Despite constant progress in in vitro fertilization (IVF) techniques and ovarian stimulation, pregnancy and embryo implantation rates remain modest . The phenomenon of embryo implantation depends both on the embryo itself and on endometrial receptivity

Detailed Description

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A favorable uterine medium is necessary for embryo implantation, but endometrial receptivity can be negatively affected by ovarian stimulation . Study of endometrial receptivity is especially limited in the context of IVF cycles .

Biopsy of the endometrium cannot be considered during the treatment, and this has encouraged the development and use of ultrasonography and Doppler-like non-invasive methods to evaluate ovarian response to the stimulation and uterine receptivity .

Conditions

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Infertility

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Transvaginal US with Doppler study

Transvaginal Ultrasound with doppler study on endometrium will be made

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

\- Maternal age from 20 to 40 years. Women with BMI range from 20 - 35 Women diagnosed with primary infertility

Exclusion Criteria

Maternal chronic medical disorder (diabetes mellitus or hypertension). Women diagnosed with autoimmune diseases or antiphospholipid syndrome
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Kasr El Aini Hospital

OTHER

Sponsor Role collaborator

National Research Centre, Egypt

OTHER

Sponsor Role collaborator

Aljazeera Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mahmoud Alalfy

Role: STUDY_CHAIR

Algazeerah hospital -Location (Giza -Egypt ) and National Research centre egypt

Locations

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Kasralainy hospital

Cairo, , Egypt

Site Status RECRUITING

Algazeerah and Kasralainy hospital

Giza, , Egypt

Site Status NOT_YET_RECRUITING

Countries

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Egypt

Central Contacts

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Mahmoud Alalfy

Role: CONTACT

01002611058

Facility Contacts

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Mahmoud Soliman

Role: primary

01222251268

Mahmoud Alalfy, master

Role: primary

+201002611058

Ahmed Elgazzar, M.D

Role: backup

+201014005959

Other Identifiers

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ICSI vascularity

Identifier Type: -

Identifier Source: org_study_id

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