Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
NCT ID: NCT05167838
Last Updated: 2022-04-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
110 participants
INTERVENTIONAL
2022-01-01
2022-07-01
Brief Summary
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Detailed Description
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Group A will undergo a day 3 fresh embryo transfer after ovarian stimulation, luteal phase support will be started just after follicular aspiration. Group B will have all of their embryo cryopreserved after ovarian stimulation with no luteal phase support after the aspiration and then undergo a frozen-thawed day 3 embryo transfer.
Controlled ovarian stimulation will be done using the gonadotropin releasing hormone (GnRH) antagonist protocol then human chorionic gonadotropin( HCG) 5000 IU trigger for final oocyte maturation.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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group A
Fresh embryo transfer group
fresh embryo transfer
55 patients undergoing fresh embryo transfer after ovarian stimulation followed by luteal phase support
Group B
Frozen embryo transfer group
Frozen embryo transfer
55 patients undergoing frozen embryo transfer after ovarian stimulation followed by cryopreservation of all embryos and transfer in another cycle.
Interventions
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fresh embryo transfer
55 patients undergoing fresh embryo transfer after ovarian stimulation followed by luteal phase support
Frozen embryo transfer
55 patients undergoing frozen embryo transfer after ovarian stimulation followed by cryopreservation of all embryos and transfer in another cycle.
Eligibility Criteria
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Inclusion Criteria
* Women ages ≥20 and \<40years old.
* BMI less than 35.
* Women who have a history of infertility.
* All patients will receive adjuvant drugs for ovulation induction (metformin from preceding cycle, cabergoline 1 tab daily for 8 days and 500 cc colloid solution on day of ovum pick up).
Exclusion Criteria
* Uterine abnormalities such as a malformed uterus (unicornuate, septate uterus), adenomyosis, submucous myoma or intrauterine adhesion.
* Severe male factor for infertility such as azoospermia.
* History of repeated ICSI trials failure.
* Women who are unable to comply with the study procedures.
20 Years
40 Years
FEMALE
Yes
Sponsors
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Cairo University
OTHER
Responsible Party
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Marwa Mohamed Mahmoud Eid
Principal investigator
Principal Investigators
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Marwa Mo Eid, MD
Role: PRINCIPAL_INVESTIGATOR
Cairo U
Locations
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Marwa Eid
Cairo, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Cairo University obgyn
Identifier Type: -
Identifier Source: org_study_id
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