Creatine Monohydrate Versus Creatine Hydrochloride on Strength and Body Composition in Elite Team-Sport Athletes
NCT ID: NCT05697900
Last Updated: 2023-01-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
48 participants
INTERVENTIONAL
2021-06-01
2022-08-22
Brief Summary
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Detailed Description
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It is important to note that the U.S. Food and Drug Administration (FDA) have recognized CrM as a safe ingredient (Generally Recognized as Safe, GRAS - No. GRN 000931). In spite of this, other forms such as creatine chloride (Cr-HCl) have been marketed as a more bioavailable sources of creatine. Since there are not studies that rigorously compare the effects of CrM versus Cr-HCl on physical performance and body composition, the aim of this study is to evaluate the effects of a 8-week supplementation protocol with the two forms of creatine (comparing to placebo) on neuromuscular strength and body composition in Colombian elite team-sport athletes.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Creatine monohydrate
5 g of creatine monohydrate per day for eight weeks
Creatine Monohydrate
The CrM group supplemented the diet with five grams of micronized creatine monohydrate per day for eight weeks. The CrM supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
Creatine hydrochloride
5 g of creatine hydrochloride per day for eight weeks
Creatine Hydrochloride
The Cr-HCl group supplemented the diet with five grams of micronized creatine monohydrate per day for eight weeks. The Cr-HCl supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
Placebo
5 g of maltodextrin per day for eight weeks
Placebo
A placebo group intakes five grams of maltodextrin daily throughout the study. The placebo supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
Interventions
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Creatine Monohydrate
The CrM group supplemented the diet with five grams of micronized creatine monohydrate per day for eight weeks. The CrM supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
Placebo
A placebo group intakes five grams of maltodextrin daily throughout the study. The placebo supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
Creatine Hydrochloride
The Cr-HCl group supplemented the diet with five grams of micronized creatine monohydrate per day for eight weeks. The Cr-HCl supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
Eligibility Criteria
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Inclusion Criteria
* Having at least one year of competitive sports training experience (including strength training at least three times a week),
* Being attended at INDEPORTES Antioquia.
Exclusion Criteria
* Those who were taking nutritional supplements (including creatine) eight weeks prior to the start of the study,
* Those who had a diagnosed pathology or health issues.
18 Years
30 Years
ALL
Yes
Sponsors
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INDEPORTES Antioquia
UNKNOWN
CES University
OTHER
Dynamical Business and Science Society - DBSS International SAS
NETWORK
Responsible Party
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Principal Investigators
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Andres Rojas-Jaramillo, PhD
Role: STUDY_DIRECTOR
INDEPORTES Antioquia
Diego A Bonilla, PhD
Role: STUDY_CHAIR
DBSS International SAS
Locations
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INDEPORTES Antioquia
Medellín, Antioquia, Colombia
Countries
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References
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Kreider RB, Jager R, Purpura M. Bioavailability, Efficacy, Safety, and Regulatory Status of Creatine and Related Compounds: A Critical Review. Nutrients. 2022 Feb 28;14(5):1035. doi: 10.3390/nu14051035.
Bonilla DA, Kreider RB, Stout JR, Forero DA, Kerksick CM, Roberts MD, Rawson ES. Metabolic Basis of Creatine in Health and Disease: A Bioinformatics-Assisted Review. Nutrients. 2021 Apr 9;13(4):1238. doi: 10.3390/nu13041238.
Juszczak E, Altman DG, Hopewell S, Schulz K. Reporting of Multi-Arm Parallel-Group Randomized Trials: Extension of the CONSORT 2010 Statement. JAMA. 2019 Apr 23;321(16):1610-1620. doi: 10.1001/jama.2019.3087.
Other Identifiers
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Acta161_N°994
Identifier Type: -
Identifier Source: org_study_id
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