Association Between Post-covid Infection Status and Perioperative Morbidity: A Ambispective Cohort Study
NCT ID: NCT05689840
Last Updated: 2024-01-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
4000 participants
OBSERVATIONAL
2022-12-01
2024-01-09
Brief Summary
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Beijing faced a wave of omicron infection starting that would result in of a wide range of population infections. At which time there is limited evidence regarding the optimal timing of surgery following SARS-CoV-2 infection especially for omiron among Chinsese patients .This study intends to explore the relationship between the incidence of postoperative complications after elective surgery and COVID-19 infection in Peking Union Medical College Hospital, and provide data support for the policy formulation of elective surgical timing for patients after COVID-19 infection.
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Detailed Description
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Conditions
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Study Design
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COHORT
OTHER
Study Groups
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0-1 week group
Patients who have been infected with Covid-19 with 0-1 week post-COVID interval before surgery.
Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
1-2 weeks group
Patients who have been infected with Covid-19 with 1-2 weeks post-COVID interval before surgery.
Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
2-3 weeks group
Patients who have been infected with Covid-19 with 2-3 weeks post-COVID interval before surgery.
Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
3-4 weeks group
Patients who have been infected with Covid-19 with 3-4 weeks post-COVID interval before surgery.
Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
4-5 weeks group
Patients who have been infected with Covid-19 with 4-5 weeks post-COVID interval before surgery.
Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
5-6 weeks group
Patients who have been infected with Covid-19 with 5-6 weeks post-COVID interval before surgery.
Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
over 6 weeks group
Patients who have been infected with Covid-19 with over 6 weeks post-COVID interval before surgery.
Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
Interventions
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Receiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
Eligibility Criteria
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Inclusion Criteria
\[The COVID-19 diagnosis is based on either (a) a positive RT-PCR nasopharyngeal swab, (b) positive antigen rest before surgery, or (c) clinical diagnosis made before surgery\].
Exclusion Criteria
2. Day surgery or outpatient surgery.
3. Patients unwilling to participate or provide COVID-19-related information.
ALL
No
Sponsors
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Peking Union Medical College Hospital
OTHER
Responsible Party
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Principal Investigators
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Shen Le, PhD
Role: STUDY_CHAIR
Peking Union Medical College Hospital
Locations
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
Countries
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References
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El-Boghdadly K, Cook TM, Goodacre T, Kua J, Denmark S, McNally S, Mercer N, Moonesinghe SR, Summerton DJ. Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update: A multidisciplinary consensus statement on behalf of the Association of Anaesthetists, Centre for Perioperative Care, Federation of Surgical Specialty Associations, Royal College of Anaesthetists, Royal College of Surgeons of England. Anaesthesia. 2022 May;77(5):580-587. doi: 10.1111/anae.15699. Epub 2022 Feb 22.
COVIDSurg Collaborative. Outcomes and Their State-level Variation in Patients Undergoing Surgery With Perioperative SARS-CoV-2 Infection in the USA: A Prospective Multicenter Study. Ann Surg. 2022 Feb 1;275(2):247-251. doi: 10.1097/SLA.0000000000005310.
Quinn KL, Huang A, Bell CM, Detsky AS, Lapointe-Shaw L, Rosella LC, Urbach DR, Razak F, Verma AA. Complications Following Elective Major Noncardiac Surgery Among Patients With Prior SARS-CoV-2 Infection. JAMA Netw Open. 2022 Dec 1;5(12):e2247341. doi: 10.1001/jamanetworkopen.2022.47341.
Bryant JM, Boncyk CS, Rengel KF, Doan V, Snarskis C, McEvoy MD, McCarthy KY, Li G, Sandberg WS, Freundlich RE. Association of Time to Surgery After COVID-19 Infection With Risk of Postoperative Cardiovascular Morbidity. JAMA Netw Open. 2022 Dec 1;5(12):e2246922. doi: 10.1001/jamanetworkopen.2022.46922.
Che L, Yu J, Jin D, Bai X, Wang Y, Zhang Y, Xu L, Shen L, Huang Y. Impact of previous COVID-19 infection on postoperative complications and functional recovery: a 1-year follow-up ambispective cohort study. Int J Surg. 2025 Jan 1;111(1):481-491. doi: 10.1097/JS9.0000000000001869.
Che L, Yu J, Bai X, Wang Y, Zhang Y, Xu L, Shen L, Huang Y. Association between post-COVID-19 status and perioperative morbidity and mortality: protocol for an ambispective cohort study. BMJ Open. 2023 Sep 14;13(9):e074337. doi: 10.1136/bmjopen-2023-074337.
Other Identifiers
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K23C0257
Identifier Type: -
Identifier Source: org_study_id
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