Describe the Effect of the Optimized Hemodialysis Technique (HDx) With Medium Cut-Off Membrane on Recovery Time and Quality of Life

NCT ID: NCT05689801

Last Updated: 2023-01-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-12-15

Study Completion Date

2024-01-15

Brief Summary

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In this study, the effect of optimizing the dialytic technique using simple questionnaires carried out in clinical routine will be described.

More specifically, the conventional dialysis technique will be combined with biofeedback software called HemoControl™. The recovery time and quality of life of patients who will use a polyethersulfone membrane (Revaclear®) and a Medium Cut-Off (MCO) membrane (Theranova®) will be observed.

The main objective is to describe the evolution of recovery time after a dialysis session in conventional hemodialysis (HD) on Revaclear® membrane and in so-called optimized hemodialysis (HDx) on MCO membrane, Theranova®.

Detailed Description

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Conditions

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Terminal Renal Insufficiency

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Patient on conventional hemodialysis then on optimized hemodialysis

Group Type EXPERIMENTAL

Questionnaire "recovery time after a dialysis session".

Intervention Type OTHER

A very short questionnaire just after the dialysis session

SF-12 questionnaire

Intervention Type OTHER

Questionnaire about quality of life of the patient

EQ-5D-5L Questionnaire

Intervention Type OTHER

Questionnaire about quality of life of the patient

Pittman, John et McIntyre questionnaire

Intervention Type OTHER

Questionnaire about quality of life of the patient under dialysis

Conventional hemodialysis

Intervention Type PROCEDURE

patient on polyethersulfone membrane dialysis (Revaclear®, Baxter) with HemoControl™ for 12 weeks

Optimized hemodialysis

Intervention Type PROCEDURE

patient on Medium Cut-Off membrane dialysis (Theranova®, Baxter) with HemoControl™ for 12 weeks.

Interventions

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Questionnaire "recovery time after a dialysis session".

A very short questionnaire just after the dialysis session

Intervention Type OTHER

SF-12 questionnaire

Questionnaire about quality of life of the patient

Intervention Type OTHER

EQ-5D-5L Questionnaire

Questionnaire about quality of life of the patient

Intervention Type OTHER

Pittman, John et McIntyre questionnaire

Questionnaire about quality of life of the patient under dialysis

Intervention Type OTHER

Conventional hemodialysis

patient on polyethersulfone membrane dialysis (Revaclear®, Baxter) with HemoControl™ for 12 weeks

Intervention Type PROCEDURE

Optimized hemodialysis

patient on Medium Cut-Off membrane dialysis (Theranova®, Baxter) with HemoControl™ for 12 weeks.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patient, male or female (using contraceptives, if of childbearing age), over 18 years of age
* Patient on conventional hemodialysis with synthetic membrane for at least 3 months
* Patient with a recovery time after the dialysis session ≥ 4 hours
* Informed patient who has signed a written consent to participate in the study
* Affiliated patient or beneficiary of a social security scheme

Exclusion Criteria

* Patient whose seniority of dialysis is less than 3 months
* Pregnant woman
* Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision
* Patient with severe cognitive impairment
* Medically unstable or frail patient
* Patient who did not sign an informed consent form accepting this research (refusal of consent or absence of signature).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ramsay Générale de Santé

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hôpital Privé Claude Galien

Quincy-sous-Sénart, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Guy Rostoker, Dr

Role: CONTACT

01 69 39 92 00

Facility Contacts

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Guy ROSTOKER, Dr

Role: primary

01 69 39 92 00

Other Identifiers

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2022-A01511-42

Identifier Type: -

Identifier Source: org_study_id

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