Clinical Evaluation of Two Toric Contact Lenses

NCT ID: NCT05688657

Last Updated: 2023-12-20

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-22

Study Completion Date

2022-12-05

Brief Summary

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The study objective was to compare short-term clinical performance data of two toric contact lenses.

Detailed Description

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The aim of this non-dispensing fitting study was to evaluate the short-term clinical performance of a monthly toric contact lens when compared to a daily disposable toric contact lens after 15 minutes of daily wear each.

Conditions

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Astigmatism

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

All participants received Lens A and then Lens B in fixed-sequence order.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Lens A

All participants wore Lens A for 15 minutes (Period 1)

Group Type EXPERIMENTAL

Lens A

Intervention Type DEVICE

Monthly Replacement Toric Silicone Hydrogel Contact Lens 15 minutes of daily wear

Lens B

All participants wore Lens B for 15 minutes (Period 2)

Group Type EXPERIMENTAL

Lens B

Intervention Type DEVICE

Daily Disposable Toric Silicone Hydrogel Contact Lens 15 minutes of daily wear

Interventions

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Lens A

Monthly Replacement Toric Silicone Hydrogel Contact Lens 15 minutes of daily wear

Intervention Type DEVICE

Lens B

Daily Disposable Toric Silicone Hydrogel Contact Lens 15 minutes of daily wear

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Is between 18 and 40 years of age (inclusive)
* Has had a self-reported visual exam in the last two years
* Is an adapted soft contact lens wearer
* Is not a habitual wearer of either study lens
* Has a contact lens spherical prescription between +4.00 to -9.00 (inclusive) best corrected visual acuity of 20/30 or better in either eye
* Have contact lens prescription of no less than -0.75D of astigmatism and no more than -2.25 D in both eyes.
* Can achieve best corrected spectacle distance visual acuity of 20/25 (0.10 logMAR) or better in each eye.
* Can achieve a distance visual acuity of 20/30 (0.18 logMAR) or better in each eye with the study contact lenses.
* Has clear corneas and no active ocular disease
* Has read, understood and signed the information consent letter.
* Patient contact lens refraction should fit within the available parameters of the study lenses.
* Is willing to comply with the wear schedule (at least 5 days per week, \> 8 hours/day assuming there are no contraindications for doing so).
* Is willing to comply with the visit schedule

Exclusion Criteria

* Has a CL prescription outside the range of the available parameters of the study lenses.
* Has a spectacle cylinder less than -0.75D or more than -2.50 D of cylinder in either eye.
* Has a history of not achieving comfortable CL wear (5 days per week; \> 8 hours/day)
* Has contact lens best corrected distance vision worse than 20/25 (0.10 logMAR) in either eye.
* Presence of clinically significant (grade 2-4) anterior segment abnormalities
* Presence of ocular or systemic disease or need of medications which might interfere with contact lens wear.
* Slit lamp findings that would contraindicate contact lens wear such as:
* Pathological dry eye or associated findings
* Pterygium, pinguecula, or corneal scars within the visual axis
* Neovascularization \> 0.75 mm in from of the limbus
* Giant papillary conjunctivitis (GCP) worse than grade 1
* Anterior uveitis or iritis (past or present)
* Seborrheic eczema, Seborrheic conjunctivitis
* History of corneal ulcers or fungal infections
* Poor personal hygiene
* Has a known history of corneal hypoesthesia (reduced corneal sensitivity)
* Has aphakia, keratoconus or a highly irregular cornea.
* Has Presbyopia or has dependence on spectacles for near work over the contact lenses.
* Has undergone corneal refractive surgery.
* Is participating in any other type of eye related clinical or research study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rubén V Guerrero, MSc., FIACLE

Role: PRINCIPAL_INVESTIGATOR

Dr. Ruben Velazquez Private Practice

Locations

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Dr. Ruben Velazquez Private Practice

Mexico City, , Mexico

Site Status

Countries

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Mexico

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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EX-MKTG-137

Identifier Type: -

Identifier Source: org_study_id