Role of 18F-FDG PET/CT in Gastric Cancer

NCT ID: NCT05687552

Last Updated: 2023-01-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-31

Study Completion Date

2024-01-31

Brief Summary

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The objective of the study is to assess the value of PET/CT in diagnosis, staging, response evaluation, and relapse monitoring of gastric cancer.

Detailed Description

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gastric cancer (GC) is the fifth most common malignancy and the third leading cause of cancer mortality worldwide (1) It carries a poor prognosis, with a 5-year survival of only 20%-30% (2) Clinical staging, based mainly on imaging, is critical in determining the best treatment.There is a widely accepted consensus of the usefulness of FDG PET/CT in staging and restaging of gastric cancer. According to evidence-based data, this modality can evaluate gastric cancer more accurately and is helpful for evaluation of tumor biologic characteristics, detection of lymph node and distant metastases, assessment of tumor response to therapy(9).

retrospective and prospective study will conducted at Sohag oncology hospital, nuclear medicine unit\& Assuit university hospital, nuclear medicine unit including 50 patients in 12 months .

Conditions

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Gastric Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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pet -ct

assessment of added value of pet -ct in patients with gastric cancer and how patient get benefit from this finding

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. patients diagnosed as GC on surgically resected specimens;
2. Patients with gastric and extragastric metastasis.
3. patients with gastric cancer either operated or not.

Exclusion Criteria

1. Patients with second malignancy.
2. Patient without proven pathology of cancer stomach.
3. Severely ill patient (patient with disturbed conscious level, or couldn't lay supine during the imaging).
4. uncontrolled diabetic patient with blood glucose level more than 200mg\\dl.
5. pregnant women
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Sara Saber Ahmed

assisstant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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wafaa elmaghraby, ass prof

Role: STUDY_DIRECTOR

Sohag University

mohamed soliman, prof

Role: STUDY_DIRECTOR

Sohag University

Central Contacts

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sara saber, ass lec

Role: CONTACT

01097661576

waleed diab, ass prof

Role: CONTACT

References

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Tang L, Wang XJ, Baba H, Giganti F. Gastric cancer and image-derived quantitative parameters: Part 2-a critical review of DCE-MRI and 18F-FDG PET/CT findings. Eur Radiol. 2020 Jan;30(1):247-260. doi: 10.1007/s00330-019-06370-x. Epub 2019 Aug 7.

Reference Type BACKGROUND
PMID: 31392480 (View on PubMed)

Saka M, Katai H, Fukagawa T, Nijjar R, Sano T. Recurrence in early gastric cancer with lymph node metastasis. Gastric Cancer. 2008;11(4):214-8. doi: 10.1007/s10120-008-0485-4. Epub 2009 Jan 8.

Reference Type BACKGROUND
PMID: 19132483 (View on PubMed)

Liu Q, Li J, Xin B, Sun Y, Feng D, Fulham MJ, Wang X, Song S. 18F-FDG PET/CT Radiomics for Preoperative Prediction of Lymph Node Metastases and Nodal Staging in Gastric Cancer. Front Oncol. 2021 Sep 13;11:723345. doi: 10.3389/fonc.2021.723345. eCollection 2021.

Reference Type RESULT
PMID: 34589429 (View on PubMed)

Other Identifiers

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gastric cancer

Identifier Type: -

Identifier Source: org_study_id

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