Two Patterns of Micropulse Laser in the Treatment of Chronic Central Serous Chorioretinopathy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-02-01

Study Completion Date

2023-12-31

Brief Summary

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Central serous chorioretinopathy (CSC) is a common eye disease mainly involving the macular area, causing central visual acuity loss. Recently, subthreshold micropulse laser used in treating chronic CSC is proved to be safe and effective. However, some studies indicate that it's less effective than half dose photodynamic therapy (PDT). Certain physicians, including us, think that this may be related to micropulse laser parameters. Thus we need to explore better laser patterns to replace PDT in treating chronic CSC. The aim of this study is to compare the treatment effect of two different patterns of laser parameters (small and regular spot diameter) in treating chronic CSC. In this randomized, double blinded, controlled trial, by comparing the subretinal fluid regression ratio, central retinal thickness, macular microvisual field, macular vascular density, chroidal volume changes and visual acuity of two groups 6 months after micropulse laser treatment, we aim to evaluate the safety and efficacy of refined micropulse laser in treating chronic CSC.

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Detailed Description

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Conditions

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Central Serous Chorioretinopathy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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100μm laser spot diameter group

Group Type EXPERIMENTAL

100μm laser spot diameter micropulse laser

Intervention Type PROCEDURE

100μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months

200μm laser spot diameter group

Group Type ACTIVE_COMPARATOR

200μm laser spot diameter micropulse laser

Intervention Type PROCEDURE

200μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months

Interventions

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100μm laser spot diameter micropulse laser

100μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months

Intervention Type PROCEDURE

200μm laser spot diameter micropulse laser

200μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients age range 18-50 years
* Patients diagnosed with chronic Central serous chorioretinopathy
* Patients have signed informed consent

Exclusion Criteria

* A history of other fundus diseases or refractive media opacity
* Patients have underwent other treatment methods for chronic Central serous chorioretinopathy
* Diopter\>-6D
* A history of system diseases such as hypertension or diabetes
* A history of using local or systemic corticosteroids

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No