Epicardial Adipose Tissue and Arterial Stiffness in People Living With Diabetes (METAB-CV-PWV)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-31

Study Completion Date

2023-03-31

Brief Summary

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The present study is a retrospective and prospective current care cohort that will allow us to evaluate the relationship between epicardial fat volume and increased arterial stiffness in a person living with diabetes.

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Detailed Description

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Epicardial adipose tissue is considered as the cardiac visceral fat and is associated with increased cardiovascular risk, for example in diabetes. Thus, the mechanisms involved seem to be related to myocardial lipotoxicity; atherosclerosis in connection with inflammation and secretion of proinflammatory factors such as cytokines but also insulin resistance.

In this context, the investigators hypothesize that epicardiac adipose tissue volume will be higher in patients with increased arterial stiffness than in those without. In this study, the investigators will then try to verify the existence of a relationship between pericardial adipose tissue volume and increased arterial stiffness in people living with diabetes.

To do this, the investigators will analyze the results of measurements of pericardial fat volume, coronary calcium score, and pulse wave velocity in diabetic patients.

Conditions

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Diabetic Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

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CT scan

coronary calcium score measurement by CT scan

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Patients will be eligible for participation in the study if:

* They are informed and have not objected to participating in the research.
* They have type 1 or 2 diabetes.
* They perform a coronary calcium score measurement by CT scan and a pulse wave velocity assessment during their routine care practice.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No