Prospective Research for Elderly (≥65 Years Old) Early Breast Cancer Patients

NCT ID: NCT05680194

Last Updated: 2023-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-04-01

Study Completion Date

2025-12-01

Brief Summary

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The elderly patients over 65 years old with breast cancer have concomitant diseases, poor tolerance to conventional treatment, and the specific prognosis of breast cancer is relatively good. Previous studies on breast cancer have almost excluded elderly breast cancer patients, and conventional treatment schemes cannot meet the clinical diagnosis and treatment needs of elderly breast cancer patients. The establishment of a prognosis model for elderly breast cancer patients can provide personalized treatment programs. This is important for prolonging the survival time of patients and improving the quality of life. This project plans to observe the relationship between prognosis and pathological staging, molecular typing, and concomitant diseases of elderly breast cancer patients in combination with immune genes, and establish a prognosis model of elderly breast cancer and verify it. This project is expected to establish a new prognostic model for elderly breast cancer patients, accurately judge the prognosis of patients, and provide a new basis for hierarchical and personalized treatment of elderly breast cancer.

Detailed Description

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Conditions

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Breast Cancer Female

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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operation

operation methods: breast-conserving surgery, mastectomy, axillary lymph node dissection, sentinal lymphnodes biopsy; chemotherapy regimens: AC, TC, AC-T/P, TCrb, TAC, capecitabine; ovarian protection:GnRHa; endocrine therapy: Aromatase inhibitor, TAM, Fulvestrant, CDK4/6 inhibitors; target therapy: trastuzumab,patuzumab, Pyrotinib.

Intervention Type PROCEDURE

Bisphosphonate

Bisphosphonate

Intervention Type DRUG

Other Intervention Names

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chemotherapy radiotherapy endocrine therapy targeted therapy

Eligibility Criteria

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Inclusion Criteria

* female patients with breast cancer
* ≥65 Years Old
* patients with breast cancer received operation in Peking Union Medical College Hospital
* treatment regimen was made in Peking Union Medical College Hospital

Exclusion Criteria

* patients with metastasis
* patietns with recurrence
* patients without pathological information
Minimum Eligible Age

65 Years

Maximum Eligible Age

100 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ying Zhong

Role: PRINCIPAL_INVESTIGATOR

Peking Union Medical College Hospital

Locations

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Peking Union Medical College Hospital

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Ying Zhong

Role: CONTACT

0086-01069158720

Xuefei Wang

Role: CONTACT

0086-01069158720

Facility Contacts

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Ying Zhong

Role: primary

0086-01069158720

Other Identifiers

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EEBC

Identifier Type: -

Identifier Source: org_study_id

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