Organosilane for Surface Cleaning in Intensive Care Units

NCT ID: NCT05673226

Last Updated: 2025-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10301 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-06

Study Completion Date

2025-01-30

Brief Summary

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The purpose of this study is to evaluate if surface disinfection with organosilane associated with traditional cleaning reduces the incidence of healthcare-associated infections (HAIs) in intensive care units when compared with traditional cleaning alone.

Detailed Description

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Conditions

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Infection, Hospital

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Randomized, controlled, cluster, crossover, trial
Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Surface disinfection with organosilane

Organosilane will be sprayed on the surfaces, using an atomizer. When the environment has been completely covered (i.e., when all surfaces and equipment have a slightly damp film), we will proceed with the second phase of the disinfection of all heavily touched surfaces. surfaces of the bed, with a microfiber cloth with organosilane.

Group Type EXPERIMENTAL

Surface disinfection with Organosilane

Intervention Type OTHER

Organosilane will be sprayed on the surfaces, using an atomizer. When the environment has been completely covered (i.e., when all surfaces and equipment have a slightly damp film), we will proceed with the second phase of the disinfection of all heavily touched surfaces. surfaces of the bed, with a microfiber cloth with organosilane.

Usual surface disinfection

The control group will perform standard cleaning and disinfection of the beds and the environment according to their previous protocols, using the usual products.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Surface disinfection with Organosilane

Organosilane will be sprayed on the surfaces, using an atomizer. When the environment has been completely covered (i.e., when all surfaces and equipment have a slightly damp film), we will proceed with the second phase of the disinfection of all heavily touched surfaces. surfaces of the bed, with a microfiber cloth with organosilane.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All patients aged 18 years and older who will be admitted to the participating ICUs

Exclusion Criteria

* Patients under 18 years
* ICUs that may use any organosilane formulation for surface disinfection
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital Sirio-Libanes

OTHER

Sponsor Role collaborator

Hospital Moinhos de Vento

OTHER

Sponsor Role collaborator

Hospital Alemão Oswaldo Cruz

OTHER

Sponsor Role collaborator

Hospital do Coracao

OTHER

Sponsor Role collaborator

Beneficência Portuguesa de São Paulo

OTHER

Sponsor Role collaborator

Hospital Israelita Albert Einstein

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hospital Jean Bittar

Belém, , Brazil

Site Status

Santa Casa de Misericórdia

Belo Horizonte, , Brazil

Site Status

Hospital de Base do Distrito Federal

Brasília, , Brazil

Site Status

Hospital Universitário de Brasília

Brasília, , Brazil

Site Status

Hospital Otoclínica

Fortaleza, , Brazil

Site Status

Hospital Geral de Goiânia

Goiânia, , Brazil

Site Status

Hospital do Tricentenário

Olinda, , Brazil

Site Status

Hospital Escola Universidade Federal de Pelotas

Pelotas, , Brazil

Site Status

Hospital Ernesto Dornelles

Porto Alegre, , Brazil

Site Status

Hospital Ana Nery

Salvador, , Brazil

Site Status

Hospital Santa Cruz

Santa Cruz do Sul, , Brazil

Site Status

Hospital Presidente Vargas

São Luís, , Brazil

Site Status

A.C. Camargo Cancer Center

São Paulo, , Brazil

Site Status

Hospital do Coração

São Paulo, , Brazil

Site Status

Countries

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Brazil

Other Identifiers

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52639521.1.1001.0071

Identifier Type: -

Identifier Source: org_study_id

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