Screening of Cardiac Abnormalities in the First Trimester of Pregnancy by Volumetric Acquisition

NCT ID: NCT05666297

Last Updated: 2022-12-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

302 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-20

Study Completion Date

2023-05-15

Brief Summary

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Ultrasound is one of the most important tools in pregnancy both for its diagnostic capacity, but also because it is not invasive.

For physiological pregnancy, the Italian guidelines provide for the execution of 3 ultrasounds: one in the first trimester (between 11 and 14 weeks), one in the second trimester (between 20 and 22 weeks) and one in the third (between 30 and 36 weeks). weeks).

Screening for cardiac abnormalities is done during second trimester ultrasound, also called structural ultrasound. However, the development of three-dimensional (3D) sonography has represented a dramatic shift in obstetrics as it allows for the acquisition of a volume of data rather than conventional planar or 2D scans. This method has allowed considerable progress in the study of the fetus in the initial stages of development and has opened new windows in the knowledge of anatomical malformations at an early age.

The possibility of detecting structural anomalies already during the first trimester of pregnancy allows, in fact, to provide the patient with additional time for counseling and for any genetic tests.

Detailed Description

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Conditions

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Pregnancy Ultrasound Fetal Conditions Cardiac Abnormalities

Keywords

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pregnancy ultrasound fetal abnormalities Cardiac Abnormalities

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients referred to the obstetric ultrasound clinic for the execution of the first trimester ultrasound between 11+0 and 13+6 weeks of gestation

Exclusion Criteria

* Less than 18 years old
* Multiple gestations
* Women with an altered state of consciousness, seriously ill, with mental handicaps;
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University of Campania Luigi Vanvitelli

OTHER

Sponsor Role lead

Responsible Party

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Antonio Schiattarella

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fabiana Savoia, MD

Role: STUDY_CHAIR

University of Campania Luigi Vanvitelli

Antonio Schiattarella, MD

Role: PRINCIPAL_INVESTIGATOR

University of Campania Luigi Vanvitelli

Locations

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University of Campania "Luigi Vanvitelli"

Naples, , Italy

Site Status

Countries

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Italy

Central Contacts

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Antonio Schiattarella, MD

Role: CONTACT

Phone: +39 3921653275

Email: [email protected]

Maddalena Morlando, MD,PhD

Role: CONTACT

Email: [email protected]

Facility Contacts

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Maddalena Morlando, MD

Role: primary

Fabiana Savoia, MD

Role: backup

Other Identifiers

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37885

Identifier Type: -

Identifier Source: org_study_id