Feasibility of Preoperative Inspiratory Muscle Training for Patients With Peritoneal Metastases

NCT ID: NCT05665257

Last Updated: 2022-12-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-30

Study Completion Date

2020-09-30

Brief Summary

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The goal of this randomized controlled feasibility study was to evaluate the feasibility of preoperative inspiratory muscle training in patients undergoing surgery because of peritoneal metastases.

The main questions it aimed to answer was how feasible the intervention is regarding process and scientific feasibility as defined by Thabane et al 2010.

Participants in the intervention group were using a handheld device to increase their inspiratory muscle strength prior to surgery and researchers compared this group to a control group who were offered a sham treatment.

Detailed Description

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Conditions

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Peritoneal Metastases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Study Groups

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Mini-PEP

Participants in the control arm were instructed to use a handheld PEP-device traditionally used to facilitate deep breathing. The PEP-device does not provide any inspiratory resistance and therefore, it was considered a sham treatment. The control group were also instructed to use the device twice a day for at least two weeks.

Group Type SHAM_COMPARATOR

Mini-PEP

Intervention Type DEVICE

Inspiratory muscle training

Participants in the intervention group were using a handheld device, Powerbreathe K3, aiming at increasing inspiratory muscle strength by applying an inspiratory resistance. They were instructed to use it twice a day for at least 14 days. Starting load was based on the baseline assessment of the participant's inspiratory muscle strength and increased during the intervention period.

Group Type EXPERIMENTAL

Inspiratory muscle training

Intervention Type DEVICE

Interventions

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Inspiratory muscle training

Intervention Type DEVICE

Mini-PEP

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Scheduled for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Exclusion Criteria

* Surgery scheduled less than two weeks from the date of inclusion
* Inability to speak and understand Swedish
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uppsala University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mikael Andersson, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University

Other Identifiers

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Ethical approval no 2016/338

Identifier Type: -

Identifier Source: org_study_id