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Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications

NCT ID: NCT05661838

Last Updated: 2022-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

272 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-08-01

Study Completion Date

2020-10-31

Brief Summary

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Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients. More than 40% of all deaths after elective spine surgery are attributed to PPCs. However, whether it influences risk of other PPCs is unclear.

Detailed Description

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Conditions

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Spinal Fusion Transfusion Pulmonary Complication

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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non-PPCs group

Patients without PPCs (Pleural effusion, Pulmonary atelectasis, Pulmonary infection)

transfusion

Intervention Type PROCEDURE

transfusion

PPCs group

Patients with PPCs (Pleural effusion, Pulmonary atelectasis, Pulmonary infection)

transfusion

Intervention Type PROCEDURE

transfusion

Interventions

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transfusion

transfusion

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients were included if they underwent elective spine surgery (e.g. multi-segmental thoracic, lumbar, or thoracolumbar spine surgery) at the Second Hospital of Zhejiang University School of Medicine from August 1, 2013 to October 31, 2020

Exclusion Criteria

* combined anterior-posterior surgery
* growth rod adjustment surgery
* spinal tumor.
* surgery took fewer than 3 hours.
Minimum Eligible Age

9 Years

Maximum Eligible Age

82 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Min Yan, doctor

Role: STUDY_CHAIR

The Second Affiliated Hospital of Zhejiang University Medical College

Locations

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The Second Affiliated Hospital of Zhejiang University anesthesiology department

Hangzhou, Zhejiang, China

Site Status

Countries

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China

Other Identifiers

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2022-0968

Identifier Type: -

Identifier Source: org_study_id