The Efficacy and Safety of the Loading Dose of Tranexamic Acid in Scoliosis Surgery During Perioperative
NCT ID: NCT04952285
Last Updated: 2021-07-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
207 participants
OBSERVATIONAL
2015-01-01
2017-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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OTHER
RETROSPECTIVE
Study Groups
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Normal saline（I）
Intravenous infusion of 0.9% saline when start to cut the skin，do not intravenous tranexamic acid during the surgery
No interventions assigned to this group
Tranexamic acid（II）
Intravenous infusion of tranexamic acid 1g when start to cut the skin in 1 hour
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiologists (ASA):I-II
* The spinal orthopedic undergoing elective surgery
Exclusion Criteria
* Blood coagulation dysfunction
* Disorders of liver and kidney function
* Tranexamic acid allergies
* The history of pulmonary embolism and venous thrombosis of lower limbs
* Anticoagulant drugs and nonsteroidal anti-inflammatory drugs in 7 days
18 Years
60 Years
ALL
No
Sponsors
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Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Responsible Party
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Other Identifiers
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2021-0215
Identifier Type: -
Identifier Source: org_study_id
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