Efficacy of Second Forward-view Examination of Left Colon for Adenoma Detection During Colonoscopy
NCT ID: NCT05651893
Last Updated: 2023-04-06
Study Results
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Basic Information
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UNKNOWN
NA
1516 participants
INTERVENTIONAL
2023-01-01
2024-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
SINGLE
Study Groups
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Second forward view examination group
After successful intubation of the cecum, the colonoscope is withdrawn to the splenic curvature with the colonic mucosa carefully inspected. Then the left colon, including the splenic curvature to the anus, is examined twice in the forward view.
re-examination
During colonoscopy, the left colon was examined a second time in the forward view.
Extended withdrawal time group
After successful intubation of the cecum, the colonoscope is withdrawn to the splenic curvature with the colonic mucosa carefully inspected. The colonoscope was withdrawn to the anus directly with withdrawal time extended to the double routine withdrawal time of the left colon.
extended withdraw time
During colonoscopy, the left colon was examined with double basic withdrawal time in the forward view.
Interventions
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re-examination
During colonoscopy, the left colon was examined a second time in the forward view.
extended withdraw time
During colonoscopy, the left colon was examined with double basic withdrawal time in the forward view.
Eligibility Criteria
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Inclusion Criteria
* Patients who have indications for screening
* Patients who have signed inform consent form.
Exclusion Criteria
* Patients with alarming signs and symptoms of colorectal cancer: hematochezia, melena, anemia, weight loss, abdominal mass, positive digital rectal examination
* Patients with abnormal blood coagulation or taking antiplatelets or anticoagulants within 7 days before colonoscopy
* Patients with inflammatory bowel diseases
* Patients with a history of abdominal surgery, or highly suspected or confirmed colorectal cancers by radiographic and laboratory tests Patients with hereditary colorectal cancer syndrome (including familial adenomatous polyposis).
* Patients with pregnancy, severe chronic cardiopulmonary and renal disease.
* Patients with failed cecal intubation
* Patients with poor BPQ that necessitated a second bowel preparation
* Patients with therapeutic colonoscopy for existing lesions
* Patients refusing to participate or to provide informed consent
45 Years
85 Years
ALL
No
Sponsors
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No.85 Hospital, Changning, Shanghai, China
OTHER
Shanxi Provincial People's Hospital
OTHER_GOV
The General Hospital of Eastern Theater Command
OTHER
The Sixth Affiliated Hospital of Guangzhou Medical University
OTHER
Fudan University
OTHER
Kunshan Hospital of Traditional Chinese Medicine
UNKNOWN
Ningjin County Hospital
UNKNOWN
Qinghai People's Hospital
OTHER
The First Affiliated Hospital of Yangtze University
OTHER
Qujing NO.1 Hospital
UNKNOWN
Jiangxi Provincial People's Hopital
OTHER
Yueyang Central Hospital
OTHER
The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
OTHER
The First People's Hospital of Changde City
OTHER
Xuzhou Central Hospital
OTHER
Wenzhou Central Hospital
OTHER
Anhui Provincial Hospital
OTHER_GOV
Jiangsu Provincial People's Hospital
OTHER
Xiangya Hospital of Central South University
OTHER
Changhai Hospital
OTHER
Responsible Party
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Zhaoshen Li
MD,Director, Head of Department of Gastroenterology and Digestive Endoscopy Center, Principal Investigator
Principal Investigators
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Zhaoshen Li, MD
Role: PRINCIPAL_INVESTIGATOR
Changhai Hospital
Locations
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Changhai Hospital, Second Military Medical University
Shanghai, , China
Countries
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Central Contacts
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Facility Contacts
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References
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Zhao S, Yang X, Wang S, Meng Q, Wang R, Bo L, Chang X, Pan P, Xia T, Yang F, Yao J, Zheng J, Sheng J, Zhao X, Tang S, Wang Y, Wang Y, Gong A, Chen W, Shen J, Zhu X, Wang S, Yan C, Yang Y, Zhu Y, Ma RJ, Wang R, Ma Y, Li Z, Bai Y. Impact of 9-Minute Withdrawal Time on the Adenoma Detection Rate: A Multicenter Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2022 Feb;20(2):e168-e181. doi: 10.1016/j.cgh.2020.11.019. Epub 2020 Nov 19.
Zhao S, Wang S, Pan P, Xia T, Chang X, Yang X, Guo L, Meng Q, Yang F, Qian W, Xu Z, Wang Y, Wang Z, Gu L, Wang R, Jia F, Yao J, Li Z, Bai Y. Magnitude, Risk Factors, and Factors Associated With Adenoma Miss Rate of Tandem Colonoscopy: A Systematic Review and Meta-analysis. Gastroenterology. 2019 May;156(6):1661-1674.e11. doi: 10.1053/j.gastro.2019.01.260. Epub 2019 Feb 6.
Other Identifiers
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SFW2022-01
Identifier Type: -
Identifier Source: org_study_id
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